Table 1.

Changes in anthropometric and metabolic variables before and after l-arginine and placebo therapy

l-ArgininePlaceboP Value
BeforeAfterBeforeAfterTime effectInteraction effect
Weight, kg105.8±3.1102.8±3.0102.1±3.698.4±3.0<0.0001<0.35
Fat mass, kg49.3±2.246.3±2.346.8±2.344.7±2.4<0.0001<0.05
Free-fat mass, kg56.5±2.056.5±1.855.3±2.253.6±2.2<0.02<0.03
Waist, cm121.1±3.0112.8±2.6116.7±2.2113.5±2.4<0.0001<0.0001
Systolic blood press, mmHg151±3128±3149±2149±2<0.0001<0.0001
Diastolic blood press, mmHg90±278±289±288±3<0.0001<0.0002
Fructosamine, μmol/l274.6±15.6220.4±8.6280.8±9.4257.8±8.7<0.0001<0.02
Fasting insulin, mU/l21.8±3.113.6±1.818.6±1.715.6±1.4<0.0002<0.04
Fasting triglycerides, mmol/l1.95±0.231.34±0.112.06±0.161.49±0.11<0.0001<0.09
Fasting FFA, mmol/l0.76±0.60.69±0.050.77±0.060.68±0.03<0.08<0.73
  • Values are means ± SE. FFA; free fatty acids.