Table 7.

Changes in hemoglobin, plasma HDL cholesterol, and PSA

Testosterone DoseBaselineWeek 20Change from BaselineP vs. Zero Change
Hemoglobin (g/l), (overall ANOVA P = 0.0001)
25 mg143.5 ± 3.5139.0 ± 2.5−5.2 ± 3.50.1759
50 mg150.8 ± 3.3146.6 ± 2.0−7.4 ± 2.30.0153
125 mg141.9 ± 2.6146.1 ± 3.12.5 ± 2.40.3061
300 mg143.5 ± 2.2149.6 ± 3.16.1 ± 2.90.0639
600 mg141.5 ± 2.3155.7 ± 2.214.2 ± 2.00.0001
PSA (ng/ml), (overall ANOVA P = 0.5290)
25 mg1.0 ± 0.21.0 ± 0.2−0.1 ± 0.20.6870
50 mg0.8 ± 0.11.1 ± 0.20.3 ± 0.10.0186
125 mg0.7 ± 0.10.8 ± 0.10.1 ± 0.10.1721
300 mg0.7 ± 0.10.9 ± 0.30.2 ± 0.20.4525
600 mg0.5 ± 0.10.7 ± 0.10.1 ± 0.00.0010
Plasma HDL cholesterol (mg/dl) (overall ANOVA P = 0.0049)
25 mg46 ± 351 ± 4+4.5 ± 2.60.1202
50 mg48 ± 347 ± 5−0.7 ± 4.00.8653
125 mg48 ± 243 ± 3−4.0 ± 1.70.0476
300 mg47 ± 341 ± 2−5.7 ± 2.80.0690
600 mg43 ± 234 ± 2−8.4 ± 1.80.0005
  • Values on each day represent the mean (±SE) of all available values on that day. However, the change from baseline represents the difference between paired values only. PSA, prostate-specific antigen; HDL, high-density lipoprotein.