Table 6.

Change in scores for sexual activity, sexual desire, and spatial cognition

Testosterone DoseBaselineTreatmentChange from BaselineP vs. zero change
Sexual activity scores (overall ANOVA P = 0.7842)
25 mg10.7 ± 1.78.2 ± 2.9−2.5 ± 3.20.4729
50 mg14.1 ± 2.113.7 ± 1.8−0.4 ± 2.80.9017
125 mg9.8 ± 2.712.0 ± 2.92.2 ± 3.10.5151
300 mg11.6 ± 1.612.0 ± 1.90.7 ± 0.90.4761
600 mg16.1 ± 3.715.6 ± 0.50.7 ± 2.20.7891
Intensity of sexual desire scores (overall ANOVA P = 0.477)
25 mg1.9 ± 0.11.3 ± 0.4−0.6 ± 0.40.2253
50 mg2.3 ± 0.12.2 ± 0.3−0.0 ± 0.30.9615
125 mg2.1 ± 0.12.0 ± 0.3−0.1 ± 0.40.9078
300 mg2.2 ± 0.22.4 ± 0.20.1 ± 0.10.3559
600 mg2.7 ± 0.22.2 ± 0.10.2 ± 0.20.4075
Spatial cognition scores
1. No. of trial levels on the checkerboard test that the participant reached before the test was terminated
(overall ANOVA P = 0.235)
25 mg6.8 ± 0.36.4 ± 0.3−0.4 ± 0.30.284
50 mg6.7 ± 0.36.7 ± 0.30.3 ± 0.30.284
125 mg6.6 ± 0.36.6 ± 0.20.0 ± 0.41.0
300 mg7.3 ± 0.26.7 ± 0.2−0.6 ± 0.30.103
600 mg6.6 ± 0.26.9 ± 0.20.3 ± 0.30.278
2. No. of checkerboard squares correctly marked in all trials (overall ANOVA P = 0.6309)
25 mg28.6 ± 2.230.4 ± 2.11.8 ± 2.10.4272
50 mg30.0 ± 2.334.7 ± 4.92.7 ± 3.50.5236
125 mg27.3 ± 3.028.1 ± 2.20.9 ± 3.80.7292
300 mg32.6 ± 2.133.3 ± 1.80.7 ± 3.10.8241
600 mg26.7 ± 2.732.5 ± 2.15.8 ± 2.20.0265
  • Values are means ± SE.