Table 1.

Subject characteristics

HbSSControl (HbAA)
Boys (n = 14)Girls (n = 14)Boys (n = 13)Girls (n = 13)
Age, yr16.2 ± 1.515.4 ± 1.315.2 ± 1.4915.0 ± 3.2
Weight, kg53.6 ± 8.651.5 ± 15.058.9 ± 12.356.4 ± 6.8
FFM, kg46.3 ± 9.640.0 ± 8.449.3 ± 8.645.0 ± 5.8
Fat mass, kg7.33 ± 5.7112.2 ± 11.69.7 ± 5.811.4 ± 3.9
Hemoglobin, g/dl8.21 ± 0.97* 8.61 ± 0.93* 13.7 ± 1.6412.9 ± 1.13
Red blood cell folate, nmol/l379 ± 163392 ± 135341 ± 183322 ± 75.5
Albumin, g/l43.0 ± 4.042.3 ± 2.541.6 ± 0.2740.5 ± 2.3
TSH, μU/ml2.08 ± 1.101.99 ± 1.061.47 ± 0.651.49 ± 0.71
Estradiol, pmol/l59.6 ± 49.892.5 ± 52.6
Testosterone, nmol/l16.2 ± 6.9721.7 ± 7.90
  • Values are means ± SD. FFM, fat-free mass; TSH, thyroid-stimulating hormone.

  • * Significantly different from control in the same gender category (independent samples t -test, P < 0.05).