Table 1.

Effect of hypophysectomy on body weight and histomorphometric indexes measured in tibial metaphysis

Animal Group Animal Wt, g Total Bone Volume, (BV/TV) % Osteoclasts, cells/mm growth plateOsteoblast Surface, mm/mm2
Intact control268 ± 21.4 22.6 ± 4.0 7.38 ± 1.01.89 ± 0.46
HX 193 ± 13.5* 5.9 ± 2.8* 3.26 ± 0.6* 0.46 ± 0.29*
  • Values are means ± SD of 10 rats/group. Total bone volume values are tibial cancellous bone volume (BV) as a percentage of total tibial volume (TV).

  • * Significant difference between age-matched intact control and hypophysectomized (HX) rats (P < 0.05) as determined by Student’s t-test.