AJP - Endocrinology and Metabolism -- Table of Contents (February 1 2010, 298 [2])

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Bernard Thorens and Mike Mueckler: Glucose transporters in the 21st Century
Am J Physiol Endocrinol Metab 298: E141-E145, 2010. First published December 15, 2009; doi:10.1152/ajpendo.00712.2009 [Abstract] [Full Text] [PDF]

ARTICLES:

Daniel J. Vis, Johan A. Westerhuis, Huub C. J. Hoefsloot, Hanno Pijl, Ferdinand Roelfsema, Jan van der Greef, and Age K. Smilde: Endocrine pulse identification using penalized methods and a minimum set of assumptions
Am J Physiol Endocrinol Metab 298: E146-E155, 2010. First published October 27, 2009; doi:10.1152/ajpendo.00048.2009 [Abstract] [Full Text] [PDF]

Yi Wang and Xinfu Guan: GLP-2 potentiates L-type Ca²⁺ channel activity associated with stimulated glucose uptake in hippocampal neurons
Am J Physiol Endocrinol Metab 298: E156-E166, 2010. First published November 17, 2009; doi:10.1152/ajpendo.00585.2009 [Abstract] [Full Text] [PDF] [Supplemental Methods]

Marion Korach-André, Paolo Parini, Lilian Larsson, Anders Arner, Knut R. Steffensen, and Jan-Åke Gustafsson: Separate and overlapping metabolic functions of LXR ${alpha}$ and LXRβ in C57Bl/6 female mice
Am J Physiol Endocrinol Metab 298: E167-E178, 2010. First published August 18, 2009; doi:10.1152/ajpendo.00184.2009 [Abstract] [Full Text] [PDF]

M. P. Sajan, G. Bandyopadhyay, A. Miura, M. L. Standaert, S. Nimal, S. L. Longnus, E. Van Obberghen, I. Hainault, F. Foufelle, R. Kahn, U. Braun, M. Leitges, and R. V. Farese: AICAR and metformin, but not exercise, increase muscle glucose transport through AMPK-, ERK-, and PDK1-dependent activation of atypical PKC
Am J Physiol Endocrinol Metab 298: E179-E192, 2010. First published November 3, 2009; doi:10.1152/ajpendo.00392.2009 [Abstract] [Full Text] [PDF]

Meng-Jie Yang, Fang Wang, Jiang-Hua Wang, Wen-Ning Wu, Zhuang-Li Hu, Jin Cheng, Dan-Fang Yu, Li-Hong Long, Hui Fu, Na Xie, and Jian-Guo Chen: PI3K integrates the effects of insulin and leptin on large-conductance Ca²⁺-activated K⁺ channels in neuropeptide Y neurons of the hypothalamic arcuate nucleus
Am J Physiol Endocrinol Metab 298: E193-E201, 2010. First published August 11, 2009; doi:10.1152/ajpendo.00155.2009 [Abstract] [Full Text] [PDF]

Yukihito Higashi, Hidehiro Matsuoka, Hidekazu Umei, Ryo Sugano, Yuichi Fujii, Junko Soga, Yasuki Kihara, Kazuaki Chayama, and Tsutomu Imaizumi: Endothelial function in subjects with isolated low HDL cholesterol: role of nitric oxide and circulating progenitor cells
Am J Physiol Endocrinol Metab 298: E202-E209, 2010. First published November 10, 2009; doi:10.1152/ajpendo.00394.2009 [Abstract] [Full Text] [PDF]

Leighton R. James, Catherine Le, and James W. Scholey: Influence of glucosamine on glomerular mesangial cell turnover: implications for hyperglycemia and hexosamine pathway flux
Am J Physiol Endocrinol Metab 298: E210-E221, 2010. First published November 10, 2009; doi:10.1152/ajpendo.00232.2009 [Abstract] [Full Text] [PDF] [Supplemental Figures]

Liaqat H. Khan, Charles R. Rosenfeld, Xiao-tie Liu, and Ronald R. Magness: Regulation of the cGMP-cPKG pathway and large-conductance Ca²⁺-activated K⁺ channels in uterine arteries during the ovine ovarian cycle
Am J Physiol Endocrinol Metab 298: E222-E228, 2010. First published November 17, 2009; doi:10.1152/ajpendo.00375.2009 [Abstract] [Full Text] [PDF] [Supplemental Figure]

Pooja Singal, Ranganath Muniyappa, Robin Chisholm, Gail Hall, Hui Chen, Michael J. Quon, and Kieren J. Mather: Simple modeling allows prediction of steady-state glucose disposal rate from early data in hyperinsulinemic glucose clamps
Am J Physiol Endocrinol Metab 298: E229-E236, 2010. First published November 17, 2009; doi:10.1152/ajpendo.00603.2009 [Abstract] [Full Text] [PDF]

Carla Schulz, Kerstin Paulus, Ralf Lobmann, Mary Dallman, and Hendrik Lehnert: Endogenous ACTH, not only ${alpha}$ -melanocyte-stimulating hormone, reduces food intake mediated by hypothalamic mechanisms
Am J Physiol Endocrinol Metab 298: E237-E244, 2010. First published November 17, 2009; doi:10.1152/ajpendo.00408.2009 [Abstract] [Full Text] [PDF]

Florence Figeac, Benjamin Uzan, Monique Faro, Noura Chelali, Bernard Portha, and Jamileh Movassat: Neonatal growth and regeneration of β-cells are regulated by the Wnt/β-catenin signaling in normal and diabetic rats
Am J Physiol Endocrinol Metab 298: E245-E256, 2010. First published November 17, 2009; doi:10.1152/ajpendo.00538.2009 [Abstract] [Full Text] [PDF]

Lars Holm, Gerrit van Hall, Adam J. Rose, Benjamin F. Miller, Simon Doessing, Erik A. Richter, and Michael Kjaer: Contraction intensity and feeding affect collagen and myofibrillar protein synthesis rates differently in human skeletal muscle
Am J Physiol Endocrinol Metab 298: E257-E269, 2010. First published November 10, 2009; doi:10.1152/ajpendo.00609.2009 [Abstract] [Full Text] [PDF]

Nimbe Torres, Claudia J. Bautista, Armando R. Tovar, Guillermo Ordáz, Maricela Rodríguez-Cruz, Victor Ortiz, Omar Granados, Peter W. Nathanielsz, Fernando Larrea, and Elena Zambrano: Protein restriction during pregnancy affects maternal liver lipid metabolism and fetal brain lipid composition in the rat
Am J Physiol Endocrinol Metab 298: E270-E277, 2010. First published November 17, 2009; doi:10.1152/ajpendo.00437.2009 [Abstract] [Full Text] [PDF]

Yukiko Kanda, Masashi Shimoda, Sumiko Hamamoto, Kazuhito Tawaramoto, Fumiko Kawasaki, Mitsuru Hashiramoto, Koji Nakashima, Michihiro Matsuki, and Kohei Kaku: Molecular mechanism by which pioglitazone preserves pancreatic β-cells in obese diabetic mice: evidence for acute and chronic actions as a PPAR ${gamma}$ agonist
Am J Physiol Endocrinol Metab 298: E278-E286, 2010. First published November 17, 2009; doi:10.1152/ajpendo.00388.2009 [Abstract] [Full Text] [PDF] [Supplemental Figures and Tables]

F. Isken, S. Klaus, K. J. Petzke, C. Loddenkemper, A. F. H. Pfeiffer, and M. O. Weickert: Impairment of fat oxidation under high- vs. low-glycemic index diet occurs before the development of an obese phenotype
Am J Physiol Endocrinol Metab 298: E287-E295, 2010. First published November 24, 2009; doi:10.1152/ajpendo.00515.2009 [Abstract] [Full Text] [PDF]

Annette E. Curtis, Jennifer H. Cooke, Jordan E. Baxter, James R. C. Parkinson, Attia Bataveljic, Mohammad A. Ghatei, Stephen R. Bloom, and Kevin G. Murphy: A kisspeptin-10 analog with greater in vivo bioactivity than kisspeptin-10
Am J Physiol Endocrinol Metab 298: E296-E303, 2010. First published November 24, 2009; doi:10.1152/ajpendo.00426.2009 [Abstract] [Full Text] [PDF]

Vicent Ribas, M. T. Audrey Nguyen, Darren C. Henstridge, Anh-Khoi Nguyen, Simon W. Beaven, Matthew J. Watt, and Andrea L. Hevener: Impaired oxidative metabolism and inflammation are associated with insulin resistance in ER ${alpha}$ -deficient mice
Am J Physiol Endocrinol Metab 298: E304-E319, 2010. First published November 17, 2009; doi:10.1152/ajpendo.00504.2009 [Abstract] [Full Text] [PDF]

Magdalena M. Przybycien-Szymanska, Yathindar S. Rao, and Toni R. Pak: Binge-pattern alcohol exposure during puberty induces sexually dimorphic changes in genes regulating the HPA axis
Am J Physiol Endocrinol Metab 298: E320-E328, 2010. First published December 1, 2009; doi:10.1152/ajpendo.00615.2009 [Abstract] [Full Text] [PDF]

Encarnación Capilla, Mònica Díaz, June Chunqiu Hou, Josep V. Planas, and Jeffrey E. Pessin: High basal cell surface levels of fish GLUT4 are related to reduced sensitivity of insulin-induced translocation toward GGA and AS160 inhibition in adipocytes
Am J Physiol Endocrinol Metab 298: E329-E336, 2010. First published December 1, 2009; doi:10.1152/ajpendo.00547.2009 [Abstract] [Full Text] [PDF]

Peilin Chen, Joan Vaughan, Cindy Donaldson, Wylie Vale, and Chien Li: Injection of Urocortin 3 into the ventromedial hypothalamus modulates feeding, blood glucose levels, and hypothalamic POMC gene expression but not the HPA axis
Am J Physiol Endocrinol Metab 298: E337-E345, 2010. First published December 1, 2009; doi:10.1152/ajpendo.00402.2009 [Abstract] [Full Text] [PDF]

Dan Zheng, Viorica Ionut, Vahe Mooradian, Darko Stefanovski, and Richard N. Bergman: Portal glucose infusion-glucose clamp measures hepatic influence on postprandial systemic glucose appearance as well as whole body glucose disposal
Am J Physiol Endocrinol Metab 298: E346-E353, 2010. First published November 24, 2009; doi:10.1152/ajpendo.00280.2009 [Abstract] [Full Text] [PDF]

Nicholas A. Burd, Jared M. Dickinson, Jennifer K. LeMoine, Chad C. Carroll, Bridget E. Sullivan, Jacob M. Haus, Bozena Jemiolo, Scott W. Trappe, Gordon M. Hughes, Charles E. Sanders, Jr., and Todd A. Trappe: Effect of a cyclooxygenase-2 inhibitor on postexercise muscle protein synthesis in humans
Am J Physiol Endocrinol Metab 298: E354-E361, 2010. First published November 24, 2009; doi:10.1152/ajpendo.00423.2009 [Abstract] [Full Text] [PDF]

Translational Physiology:

Lei Gu, Guo-Fang Zhang, Rajan S. Kombu, Frederick Allen, Gerd Kutz, Wolf-Ulrich Brewer, Charles R. Roe, and Henri Brunengraber: Parenteral and enteral metabolism of anaplerotic triheptanoin in normal rats. II. Effects on lipolysis, glucose production, and liver acyl-CoA profile
Am J Physiol Endocrinol Metab 298: E362-E371, 2010. First published November 10, 2009; doi:10.1152/ajpendo.00384.2009 [Abstract] [Full Text] [PDF]

Letter to the Editor:

Wenhong Cao, Hui-Yu Liu, Tao Hong, and Zhenqi Liu: Excess exposure to insulin may be the primary cause of insulin resistance
Am J Physiol Endocrinol Metab 298: E372-E372, 2010; doi:10.1152/ajpendo.00677.2009 [Full Text] [PDF]

CORRIGENDUM:

: Corrigendum
Am J Physiol Endocrinol Metab 298: E373-E373, 2010; doi:10.1152/ajpendo.zh1-5922-corr.2010 [Full Text] [PDF]

Cover Caption:

Cover

Cover: Glucose uptake in living hippocampal neurons. A fluorescent, nonmetabolized glucose analog {6-[N(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino]-6-deoxyglucose (6-NBDG)} was used to trace glucose uptake and transport by living neurons. 6-NBDG (300 μM) was loaded to primary neurons on DIV 6 and was detected immediately after washout. The intracellular accumulation of 6-NBDG (in green) suggests that glucose is directly taken up by primary neurons. From: Wang Y, Guan X. GLP-2 potentiates L-type Ca²⁺ channel activity associated with stimulated glucose uptake in hippocampal neurons. Am J Physiol Endocrinol Metab 298: E156–E166, 2010.