REVIEW:

Luigi Laviola, Annalisa Natalicchio, Sebastio Perrini, and Francesco Giorgino

Abnormalities of IGF-I signaling in the pathogenesis of diseases of the bone, brain, and fetoplacental unit in humans
Am J Physiol Endocrinol Metab 295: E991-E999, 2008. First published August 19, 2008; doi:10.1152/ajpendo.90452.2008 [Abstract] [Full Text] [PDF]  

Alessandro Laviano, Akio Inui, Daniel L. Marks, Michael M. Meguid, Claude Pichard, Filippo Rossi Fanelli, and Marilia Seelaender

Neural control of the anorexia-cachexia syndrome
Am J Physiol Endocrinol Metab 295: E1000-E1008, 2008. First published August 19, 2008; doi:10.1152/ajpendo.90252.2008 [Abstract] [Full Text] [PDF]  

Jose E. Galgani, Cedric Moro, and Eric Ravussin

Metabolic flexibility and insulin resistance
Am J Physiol Endocrinol Metab 295: E1009-E1017, 2008. First published September 2, 2008; doi:10.1152/ajpendo.90558.2008 [Abstract] [Full Text] [PDF]  

ARTICLES:

Sheila R. Costford, Shehla N. Chaudhry, Sean A. Crawford, Mahmoud Salkhordeh, and Mary-Ellen Harper

Long-term high-fat feeding induces greater fat storage in mice lacking UCP3
Am J Physiol Endocrinol Metab 295: E1018-E1024, 2008. First published August 19, 2008; doi:10.1152/ajpendo.00779.2007 [Abstract] [Full Text] [PDF]  

Takahiro J. Nakamura, Michael T. Sellix, Michael Menaker, and Gene D. Block

Estrogen directly modulates circadian rhythms of PER2 expression in the uterus
Am J Physiol Endocrinol Metab 295: E1025-E1031, 2008. First published August 26, 2008; doi:10.1152/ajpendo.90392.2008 [Abstract] [Full Text] [PDF]  

Elaine Vieira, Elisabeth C. Nilsson, Annika Nerstedt, Mattias Ormestad, Yun Chau Long, Pablo M. Garcia-Roves, Juleen R. Zierath, and Margit Mahlapuu

Relationship between AMPK and the transcriptional balance of clock-related genes in skeletal muscle
Am J Physiol Endocrinol Metab 295: E1032-E1037, 2008. First published August 26, 2008; doi:10.1152/ajpendo.90510.2008 [Abstract] [Full Text] [PDF]  

Dong-Hoon Kim, Darleen Sandoval, Jacquelyn A. Reed, Emily K. Matter, Emeline G. Tolod, Stephen C. Woods, and Randy J. Seeley

The role of GM-CSF in adipose tissue inflammation
Am J Physiol Endocrinol Metab 295: E1038-E1046, 2008. First published September 2, 2008; doi:10.1152/ajpendo.00061.2008 [Abstract] [Full Text] [PDF] [Supplemental Figures]  

Midori Kayahara, Jacqueline Ohanian, Vasken Ohanian, Andrew Berry, Ratna Vadlamudi, and David W. Ray

MNAR functionally interacts with both NH₂- and COOH-terminal GR domains to modulate transactivation
Am J Physiol Endocrinol Metab 295: E1047-E1055, 2008. First published August 5, 2008; doi:10.1152/ajpendo.90429.2008 [Abstract] [Full Text] [PDF]  

Olga Gealekman, Alison Burkart, My Chouinard, Sarah M. Nicoloro, Juerg Straubhaar, and Silvia Corvera

Enhanced angiogenesis in obesity and in response to PPAR activators through adipocyte VEGF and ANGPTL4 production
Am J Physiol Endocrinol Metab 295: E1056-E1064, 2008. First published August 26, 2008; doi:10.1152/ajpendo.90345.2008 [Abstract] [Full Text] [PDF]  

Craig S. Nunemaker, Meng Chen, Hong Pei, Sarah D. Kimble, Susanna R. Keller, Jeffrey D. Carter, Zandong Yang, Kellie M. Smith, Runpei Wu, Melissa H. Bevard, James C. Garmey, and Jerry L. Nadler

12-Lipoxygenase-knockout mice are resistant to inflammatory effects of obesity induced by western diet
Am J Physiol Endocrinol Metab 295: E1065-E1075, 2008. First published September 9, 2008; doi:10.1152/ajpendo.90371.2008 [Abstract] [Full Text] [PDF]  

Lindsey N. Sutherland, Lauren C. Capozzi, N. Joan Turchinsky, Rhonda C. Bell, and David C. Wright

Time course of high-fat diet-induced reductions in adipose tissue mitochondrial proteins: potential mechanisms and the relationship to glucose intolerance
Am J Physiol Endocrinol Metab 295: E1076-E1083, 2008. First published September 9, 2008; doi:10.1152/ajpendo.90408.2008 [Abstract] [Full Text] [PDF]  

Stefan Schmidt, Miriam Richter, Dirk Montag, Tina Sartorius, Verena Gawlik, Anita M. Hennige, Stephan Scherneck, Heinz Himmelbauer, Stefan Z. Lutz, Robert Augustin, Reinhart Kluge, Peter Ruth, Hans-Georg Joost, and Annette Schürmann

Neuronal functions, feeding behavior, and energy balance in Slc2a3^+/– mice
Am J Physiol Endocrinol Metab 295: E1084-E1094, 2008. First published September 9, 2008; doi:10.1152/ajpendo.90491.2008 [Abstract] [Full Text] [PDF] [Supplemental Figures]  

Giuseppe Murdolo, Christian Herder, Zhaohui Wang, Bettina Rose, Martin Schmelz, and Per-Anders Jansson

In situ profiling of adipokines in subcutaneous microdialysates from lean and obese individuals
Am J Physiol Endocrinol Metab 295: E1095-E1105, 2008. First published September 9, 2008; doi:10.1152/ajpendo.90483.2008 [Abstract] [Full Text] [PDF]  

You-Guo Niu and Rhys D. Evans

Metabolism of very-low-density lipoprotein and chylomicrons by streptozotocin-induced diabetic rat heart: effects of diabetes and lipoprotein preference
Am J Physiol Endocrinol Metab 295: E1106-E1116, 2008. First published September 9, 2008; doi:10.1152/ajpendo.90260.2008 [Abstract] [Full Text] [PDF]  

L. Attig, J. Djiane, A. Gertler, O. Rampin, T. Larcher, S. Boukthir, P. M. Anton, J. Y. Madec, I. Gourdou, and L. Abdennebi-Najar

Study of hypothalamic leptin receptor expression in low-birth-weight piglets and effects of leptin supplementation on neonatal growth and development
Am J Physiol Endocrinol Metab 295: E1117-E1125, 2008. First published September 9, 2008; doi:10.1152/ajpendo.90542.2008 [Abstract] [Full Text] [PDF]  

Kelly B. Scribner, Dorota B. Pawlak, Cristin M. Aubin, Joseph A. Majzoub, and David S. Ludwig

Long-term effects of dietary glycemic index on adiposity, energy metabolism, and physical activity in mice
Am J Physiol Endocrinol Metab 295: E1126-E1131, 2008. First published September 9, 2008; doi:10.1152/ajpendo.90487.2008 [Abstract] [Full Text] [PDF]  

Sherley Visinoni, Barbara C. Fam, Amy Blair, Christian Rantzau, Benjamin J. Lamont, Russell Bouwman, Matthew J. Watt, Joseph Proietto, Jenny M. Favaloro, and Sofianos Andrikopoulos

Increased glucose production in mice overexpressing human fructose-1,6-bisphosphatase in the liver
Am J Physiol Endocrinol Metab 295: E1132-E1141, 2008. First published September 9, 2008; doi:10.1152/ajpendo.90552.2008 [Abstract] [Full Text] [PDF]  

Helen Cho, Shawn C. Black, David Looper, Manli Shi, Dawn Kelly-Sullivan, Sergei Timofeevski, Karen Siegel, Xiao-Hong Yu, Scott R. McDonnell, Ping Chen, Junming Yie, Kathleen M. Ogilvie, James Fraser, and Celia P. Briscoe

Pharmacological characterization of a small molecule inhibitor of c-Jun kinase
Am J Physiol Endocrinol Metab 295: E1142-E1151, 2008. First published August 26, 2008; doi:10.1152/ajpendo.90298.2008 [Abstract] [Full Text] [PDF]  

Chiara Dalla Man, Gianna Toffolo, Rita Basu, Robert A. Rizza, and Claudio Cobelli

Use of labeled oral minimal model to measure hepatic insulin sensitivity
Am J Physiol Endocrinol Metab 295: E1152-E1159, 2008. First published September 2, 2008; doi:10.1152/ajpendo.00486.2007 [Abstract] [Full Text] [PDF]  

June Zhou, Roy J. Martin, Richard T. Tulley, Anne M. Raggio, Kathleen L. McCutcheon, Li Shen, Samuel Colby Danna, Sasmita Tripathy, Maren Hegsted, and Michael J. Keenan

Dietary resistant starch upregulates total GLP-1 and PYY in a sustained day-long manner through fermentation in rodents
Am J Physiol Endocrinol Metab 295: E1160-E1166, 2008. First published September 16, 2008; doi:10.1152/ajpendo.90637.2008 [Abstract] [Full Text] [PDF]  

R. Teruyama, D. L. Lipschitz, L. Wang, G. R. Ramoz, W. R. Crowley, S. L. Bealer, and W. E. Armstrong

Central blockade of oxytocin receptors during mid-late gestation reduces amplitude of slow afterhyperpolarization in supraoptic oxytocin neurons
Am J Physiol Endocrinol Metab 295: E1167-E1171, 2008. First published September 23, 2008; doi:10.1152/ajpendo.90620.2008 [Abstract] [Full Text] [PDF]  

Kristen E. Govoni, Jon E. Wergedal, Robert B. Chadwick, Apurva K. Srivastava, and Subburaman Mohan

Prepubertal OVX increases IGF-I expression and bone accretion in C57BL/6J mice
Am J Physiol Endocrinol Metab 295: E1172-E1180, 2008. First published September 23, 2008; doi:10.1152/ajpendo.90507.2008 [Abstract] [Full Text] [PDF]  

Emilie Vazeille, Audrey Codran, Agnès Claustre, Julien Averous, Anne Listrat, Daniel Béchet, Daniel Taillandier, Dominique Dardevet, Didier Attaix, and Lydie Combaret

The ubiquitin-proteasome and the mitochondria-associated apoptotic pathways are sequentially downregulated during recovery after immobilization-induced muscle atrophy
Am J Physiol Endocrinol Metab 295: E1181-E1190, 2008. First published September 23, 2008; doi:10.1152/ajpendo.90532.2008 [Abstract] [Full Text] [PDF]  

Taku Nedachi, Hideaki Fujita, and Makoto Kanzaki

Contractile C₂C₁₂ myotube model for studying exercise-inducible responses in skeletal muscle
Am J Physiol Endocrinol Metab 295: E1191-E1204, 2008. First published September 9, 2008; doi:10.1152/ajpendo.90280.2008 [Abstract] [Full Text] [PDF] [Supplemental Videos]  

Utpal Sen, Walter E. Rodriguez, Neetu Tyagi, Munish Kumar, Soumi Kundu, and Suresh C. Tyagi

Ciglitazone, a PPAR agonist, ameliorates diabetic nephropathy in part through homocysteine clearance
Am J Physiol Endocrinol Metab 295: E1205-E1212, 2008. First published September 9, 2008; doi:10.1152/ajpendo.90534.2008 [Abstract] [Full Text] [PDF]  

Joshua F. Yarrow, Christine F. Conover, Amol V. Purandare, Ashish M. Bhakta, Naiquan Zheng, Bryan Conrad, Molly K. Altman, Sarah E. Franz, Thomas J. Wronski, and Stephen E. Borst

Supraphysiological testosterone enanthate administration prevents bone loss and augments bone strength in gonadectomized male and female rats
Am J Physiol Endocrinol Metab 295: E1213-E1222, 2008. First published September 9, 2008; doi:10.1152/ajpendo.90640.2008 [Abstract] [Full Text] [PDF]  

TRANSLATIONAL PHYSIOLOGY:

Graeme Eisenhofer, Thanh-Truc Huynh, Abdel Elkahloun, John C. Morris, Gennady Bratslavsky, W. Marston Linehan, Zhengping Zhuang, Brian M. Balgley, Cheng S. Lee, Massimo Mannelli, Jacques W. M. Lenders, Stefan R. Bornstein, and Karel Pacak

Differential expression of the regulated catecholamine secretory pathway in different hereditary forms of pheochromocytoma
Am J Physiol Endocrinol Metab 295: E1223-E1233, 2008. First published October 14, 2008; doi:10.1152/ajpendo.90591.2008 [Abstract] [Full Text] [PDF]  

Lin Tian, Cai Li, Jiping Qi, Peng Fu, Xiaoyan Yu, Xiaokun Li, and Lu Cai

Diabetes-induced upregulation of urotensin II and its receptor plays an important role in TGF-β1-mediated renal fibrosis and dysfunction
Am J Physiol Endocrinol Metab 295: E1234-E1242, 2008. First published September 16, 2008; doi:10.1152/ajpendo.90672.2008 [Abstract] [Full Text] [PDF]  

Ganesh V. Sangle, Ruozhi Zhao, and Garry X. Shen

Transmembrane signaling pathway mediates oxidized low-density lipoprotein-induced expression of plasminogen activator inhibitor-1 in vascular endothelial cells
Am J Physiol Endocrinol Metab 295: E1243-E1254, 2008. First published September 16, 2008; doi:10.1152/ajpendo.90415.2008 [Abstract] [Full Text] [PDF]  

INNOVATIVE METHODOLOGY:

Abdul Jaleel, Kevin R. Short, Yan W. Asmann, Katherine A. Klaus, Dawn M. Morse, G. Charles Ford, and K. Sreekumaran Nair

In vivo measurement of synthesis rate of individual skeletal muscle mitochondrial proteins
Am J Physiol Endocrinol Metab 295: E1255-E1268, 2008. First published September 2, 2008; doi:10.1152/ajpendo.90586.2008 [Abstract] [Full Text] [PDF] [Supplemental Tables]  

J. Cacho, J. Sevillano, J. de Castro, E. Herrera, and M. P. Ramos

Validation of simple indexes to assess insulin sensitivity during pregnancy in Wistar and Sprague-Dawley rats
Am J Physiol Endocrinol Metab 295: E1269-E1276, 2008. First published September 16, 2008; doi:10.1152/ajpendo.90207.2008 [Abstract] [Full Text] [PDF]  

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