AJP - Endocrinology and Metabolism -- Table of Contents (July 1 2008, 295 [1])

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EDITORIAL FOCUS:

Patricia E. Molina: Alcohol—intoxicating roadblocks and bottlenecks in hepatic protein and lipid metabolism
Am J Physiol Endocrinol Metab 295: E1-E2, 2008. First published May 13, 2008; doi:10.1152/ajpendo.90412.2008 [Full Text] [PDF]

Anne M. Karinch, Jonathan H. Martin, and Thomas C. Vary: Acute and chronic ethanol consumption differentially impact pathways limiting hepatic protein synthesis
Am J Physiol Endocrinol Metab 295: E3-E9, 2008. First published March 11, 2008; doi:10.1152/ajpendo.00026.2008 [Abstract] [Full Text] [PDF]

Margaret Sozio and David W. Crabb: Alcohol and lipid metabolism
Am J Physiol Endocrinol Metab 295: E10-E16, 2008. First published March 18, 2008; doi:10.1152/ajpendo.00011.2008 [Abstract] [Full Text] [PDF]

REVIEWS:

Ronald J. Copeland, John W. Bullen, and Gerald W. Hart: Cross-talk between GlcNAcylation and phosphorylation: roles in insulin resistance and glucose toxicity
Am J Physiol Endocrinol Metab 295: E17-E28, 2008. First published April 29, 2008; doi:10.1152/ajpendo.90281.2008 [Abstract] [Full Text] [PDF] [Supplemental Table]

Kei Sakamoto and Geoffrey D. Holman: Emerging role for AS160/TBC1D4 and TBC1D1 in the regulation of GLUT4 traffic
Am J Physiol Endocrinol Metab 295: E29-E37, 2008. First published May 13, 2008; doi:10.1152/ajpendo.90331.2008 [Abstract] [Full Text] [PDF]

ARTICLES:

Nam Ho Jeoung and Robert A. Harris: Pyruvate dehydrogenase kinase-4 deficiency lowers blood glucose and improves glucose tolerance in diet-induced obese mice
Am J Physiol Endocrinol Metab 295: E46-E54, 2008. First published April 22, 2008; doi:10.1152/ajpendo.00536.2007 [Abstract] [Full Text] [PDF]

M. Rajagopal, H. Fischer, and J. H. Widdicombe: Hormonal and purinergic stimulation of bicarbonate secretion in oviducts of rhesus monkey
Am J Physiol Endocrinol Metab 295: E55-E62, 2008. First published April 22, 2008; doi:10.1152/ajpendo.00714.2007 [Abstract] [Full Text] [PDF]

Daniel I. Spratt, Robert S. Kramer, Jeremy R. Morton, F. Lee Lucas, Karen Becker, and Christopher Longcope: Characterization of a prospective human model for study of the reproductive hormone responses to major illness
Am J Physiol Endocrinol Metab 295: E63-E69, 2008. First published April 15, 2008; doi:10.1152/ajpendo.00472.2007 [Abstract] [Full Text] [PDF]

Milou Beelen, René Koopman, Annemie P. Gijsen, Hanne Vandereyt, Arie K. Kies, Harm Kuipers, Wim H. M. Saris, and Luc J. C. van Loon: Protein coingestion stimulates muscle protein synthesis during resistance-type exercise
Am J Physiol Endocrinol Metab 295: E70-E77, 2008. First published April 22, 2008; doi:10.1152/ajpendo.00774.2007 [Abstract] [Full Text] [PDF]

Sabine Strassburg, Stefan D. Anker, Tamara R. Castaneda, Lukas Burget, Diego Perez-Tilve, Paul T. Pfluger, Ruben Nogueiras, Heather Halem, Jesse Z. Dong, Michael D. Culler, Rakesh Datta, and Matthias H. Tschöp: Long-term effects of ghrelin and ghrelin receptor agonists on energy balance in rats
Am J Physiol Endocrinol Metab 295: E78-E84, 2008. First published May 6, 2008; doi:10.1152/ajpendo.00040.2008 [Abstract] [Full Text] [PDF]

Ksenia Sevastianova, Jussi Sutinen, Katja Kannisto, Anders Hamsten, Matti Ristola, and Hannele Yki-Järvinen: Adipose tissue inflammation and liver fat in patients with highly active antiretroviral therapy-associated lipodystrophy
Am J Physiol Endocrinol Metab 295: E85-E91, 2008. First published April 22, 2008; doi:10.1152/ajpendo.90224.2008 [Abstract] [Full Text] [PDF]

Séverine M. A. Pascal, Yves Guiot, Stella Pelengaris, Michael Khan, and Jean-Christophe Jonas: Effects of c-MYC activation on glucose stimulus-secretion coupling events in mouse pancreatic islets
Am J Physiol Endocrinol Metab 295: E92-E102, 2008. First published April 15, 2008; doi:10.1152/ajpendo.90235.2008 [Abstract] [Full Text] [PDF] [Supplemental Tables]

Adam Whaley-Connell, Javad Habibi, Shawna A. Cooper, Vincent G. DeMarco, Melvin R. Hayden, Craig S. Stump, Daniel Link, Carlos M. Ferrario, and James R. Sowers: Effect of renin inhibition and AT₁R blockade on myocardial remodeling in the transgenic Ren2 rat
Am J Physiol Endocrinol Metab 295: E103-E109, 2008. First published May 6, 2008; doi:10.1152/ajpendo.00752.2007 [Abstract] [Full Text] [PDF]

Guido Lastra, Adam Whaley-Connell, Camila Manrique, Javad Habibi, Alex A. Gutweiler, Lama Appesh, Melvin R. Hayden, Yongzhong Wei, Carlos Ferrario, and James R. Sowers: Low-dose spironolactone reduces reactive oxygen species generation and improves insulin-stimulated glucose transport in skeletal muscle in the TG(mRen2)27 rat
Am J Physiol Endocrinol Metab 295: E110-E116, 2008. First published April 29, 2008; doi:10.1152/ajpendo.00258.2007 [Abstract] [Full Text] [PDF]

Hsien-Yu Peng, Hung-Ming Chang, Sarah Y. Chang, Kwong-Chung Tung, Shin-Da Lee, Dylan Chou, Cheng-Yuan Lai, Chun-Hsien Chiu, Gin-Den Chen, and Tzer-Bin Lin: Orexin-A modulates glutamatergic NMDA-dependent spinal reflex potentiation via inhibition of NR2B subunit
Am J Physiol Endocrinol Metab 295: E117-E129, 2008. First published May 13, 2008; doi:10.1152/ajpendo.90243.2008 [Abstract] [Full Text] [PDF]

K. J. Suter and L. O'Farrell: Impaired episodic LH secretion in female mice with GFP in GnRH neurons
Am J Physiol Endocrinol Metab 295: E130-E136, 2008. First published May 27, 2008; doi:10.1152/ajpendo.90300.2008 [Abstract] [Full Text] [PDF]

Girish Kewalramani, Prasanth Puthanveetil, Min Suk Kim, Fang Wang, Vivian Lee, Nathania Hau, Elham Beheshti, Natalie Ng, Ashraf Abrahani, and Brian Rodrigues: Acute dexamethasone-induced increase in cardiac lipoprotein lipase requires activation of both Akt and stress kinases
Am J Physiol Endocrinol Metab 295: E137-E147, 2008. First published May 6, 2008; doi:10.1152/ajpendo.00004.2008 [Abstract] [Full Text] [PDF]

Linda Mustelin, Kirsi H. Pietiläinen, Aila Rissanen, Anssi R. Sovijärvi, Päivi Piirilä, Jussi Naukkarinen, Leena Peltonen, Jaakko Kaprio, and Hannele Yki-Järvinen: Acquired obesity and poor physical fitness impair expression of genes of mitochondrial oxidative phosphorylation in monozygotic twins discordant for obesity
Am J Physiol Endocrinol Metab 295: E148-E154, 2008. First published May 6, 2008; doi:10.1152/ajpendo.00580.2007 [Abstract] [Full Text] [PDF]

Julie A. Harney and Robert L. Rodgers: Insulin-like stimulation of cardiac fuel metabolism by physiological levels of glucagon: involvement of PI3K but not cAMP
Am J Physiol Endocrinol Metab 295: E155-E161, 2008. First published May 20, 2008; doi:10.1152/ajpendo.90228.2008 [Abstract] [Full Text] [PDF]

V. Kaddai, T. Gonzalez, M. Bolla, Y. Le Marchand-Brustel, and M. Cormont: The nitric oxide-donating derivative of acetylsalicylic acid, NCX 4016, stimulates glucose transport and glucose transporters translocation in 3T3-L1 adipocytes
Am J Physiol Endocrinol Metab 295: E162-E169, 2008. First published May 20, 2008; doi:10.1152/ajpendo.00622.2007 [Abstract] [Full Text] [PDF]

Kathryn L. Gatford, Julie A. Owens, Shaofu Li, Timothy J. M. Moss, John P. Newnham, John R. G. Challis, and Deborah M. Sloboda: Repeated betamethasone treatment of pregnant sheep programs persistent reductions in circulating IGF-I and IGF-binding proteins in progeny
Am J Physiol Endocrinol Metab 295: E170-E178, 2008. First published May 20, 2008; doi:10.1152/ajpendo.00047.2008 [Abstract] [Full Text] [PDF]

Céline Fernandez, Ola Hansson, Pernilla Nevsten, Cecilia Holm, and Cecilia Klint: Hormone-sensitive lipase is necessary for normal mobilization of lipids during submaximal exercise
Am J Physiol Endocrinol Metab 295: E179-E186, 2008. First published May 20, 2008; doi:10.1152/ajpendo.00282.2007 [Abstract] [Full Text] [PDF] [Supplemental Figures and Tables]

Fiona A. Wilson, Renán A. Orellana, Agus Suryawan, Hanh V. Nguyen, Asumthia S. Jeyapalan, Jason Frank, and Teresa A. Davis: Stimulation of muscle protein synthesis by somatotropin in pigs is independent of the somatotropin-induced increase in circulating insulin
Am J Physiol Endocrinol Metab 295: E187-E194, 2008. First published May 6, 2008; doi:10.1152/ajpendo.90253.2008 [Abstract] [Full Text] [PDF]

Vladimir Ljubicic and David A. Hood: Kinase-specific responsiveness to incremental contractile activity in skeletal muscle with low and high mitochondrial content
Am J Physiol Endocrinol Metab 295: E195-E204, 2008. First published May 20, 2008; doi:10.1152/ajpendo.90276.2008 [Abstract] [Full Text] [PDF]

Yu Wu and Cynthia M. Smas: Wdnm1-like, a new adipokine with a role in MMP-2 activation
Am J Physiol Endocrinol Metab 295: E205-E215, 2008. First published May 20, 2008; doi:10.1152/ajpendo.90316.2008 [Abstract] [Full Text] [PDF] [Supplemental Table]

INNOVATIVE METHODOLOGY:

Celvie L. Yuan, Naveen Sharma, Danielle A. Gilge, William C. Stanley, Yi Li, Maria Hatzoglou, and Stephen F. Previs: Preserved protein synthesis in the heart in response to acute fasting and chronic food restriction despite reductions in liver and skeletal muscle
Am J Physiol Endocrinol Metab 295: E216-E222, 2008. First published April 29, 2008; doi:10.1152/ajpendo.00545.2007 [Abstract] [Full Text] [PDF]

CORRIGENDA:

: CORRIGENDUM
Am J Physiol Endocrinol Metab 295: E223-E223, 2008; doi:10.1152/ajpendo.zh1-5359-corr.2008 [Full Text] [PDF]

PERSPECTIVES:

Eddy Karnieli and Michal Armoni: Transcriptional regulation of the insulin-responsive glucose transporter GLUT4 gene: from physiology to pathology
Am J Physiol Endocrinol Metab 295: E38-E45, 2008. First published May 20, 2008; doi:10.1152/ajpendo.90306.2008 [Abstract] [Full Text] [PDF]

Cover Caption:

Cover

Cover: Islets of Langerhans in the pancreas of a 3-mo-old wild-type mouse (C57BL/6J × CBA F₁ genetic background). A 4-μm-thick section of the pancreas fixed in Bouin's fluid and embedded in paraffin was stained with hematoxylin-eosin. The image was obtained with an Axioplan microscope (×20 objective) coupled to an Axiocam HRc digital camera. From Pascal SM, Guiot Y, Pelengaris S, Khan M, Jonas J. Effects of c-MYC activation on glucose stimulus-secretion coupling events in mouse pancreatic islets. Am J Physiol Endocrinol Metab 295: E92–E102, 2008.