AJP - Endocrinology and Metabolism -- Table of Contents (August 1 2007, 293 [2])

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EDITORIAL:

Amira Klip: Pushing the frontiers of endocrinology and metabolism: a new Perspectives series
Am J Physiol Endocrinol Metab 293: E443-E443, 2007. First published April 24, 2007; doi:10.1152/ajpendo.00257.2007 [Full Text] [PDF]

INVITED REVIEWS:

Jan Nedergaard, Tore Bengtsson, and Barbara Cannon: Unexpected evidence for active brown adipose tissue in adult humans
Am J Physiol Endocrinol Metab 293: E444-E452, 2007. First published May 1, 2007; doi:10.1152/ajpendo.00691.2006 [Abstract] [Full Text] [PDF]

FRONTIERS:

Charles H. Lang, Robert A. Frost, and Thomas C. Vary: Regulation of muscle protein synthesis during sepsis and inflammation
Am J Physiol Endocrinol Metab 293: E453-E459, 2007. First published May 15, 2007; doi:10.1152/ajpendo.00204.2007 [Abstract] [Full Text] [PDF]

Philip E. Dubé and Patricia L. Brubaker: Frontiers in glucagon-like peptide-2: multiple actions, multiple mediators
Am J Physiol Endocrinol Metab 293: E460-E465, 2007. First published July 24, 2007; doi:10.1152/ajpendo.00149.2007 [Abstract] [Full Text] [PDF]

ARTICLES:

F. Dadoun, P. Darmon, V. Achard, S. Boullu-Ciocca, F. Philip-Joet, M. C. Alessi, M. Rey, M. Grino, and A. Dutour: Effect of sleep apnea syndrome on the circadian profile of cortisol in obese men
Am J Physiol Endocrinol Metab 293: E466-E474, 2007. First published May 15, 2007; doi:10.1152/ajpendo.00126.2007 [Abstract] [Full Text] [PDF]

Jinming Li, Jaclyn Quirt, Hung Quoc Do, Kristina Lyte, Fraser Fellows, Cynthia G. Goodyer, and Rennian Wang: Expression of c-Kit receptor tyrosine kinase and effect on $beta$ -cell development in the human fetal pancreas
Am J Physiol Endocrinol Metab 293: E475-E483, 2007. First published May 22, 2007; doi:10.1152/ajpendo.00172.2007 [Abstract] [Full Text] [PDF] [Supplemental Figure]

L. K. Saxon, A. G. Robling, A. B. Castillo, S. Mohan, and C. H. Turner: The skeletal responsiveness to mechanical loading is enhanced in mice with a null mutation in estrogen receptor- $beta$
Am J Physiol Endocrinol Metab 293: E484-E491, 2007. First published May 29, 2007; doi:10.1152/ajpendo.00189.2007 [Abstract] [Full Text] [PDF]

Kimberly R. Coenen and Alyssa H. Hasty: Obesity potentiates development of fatty liver and insulin resistance, but not atherosclerosis, in high-fat diet-fed agouti LDLR-deficient mice
Am J Physiol Endocrinol Metab 293: E492-E499, 2007. First published June 12, 2007; doi:10.1152/ajpendo.00171.2007 [Abstract] [Full Text] [PDF]

R. Scott Rector, Shana O. Warner, Ying Liu, Pamela S. Hinton, Grace Y. Sun, Richard H. Cox, Craig S. Stump, M. Harold Laughlin, Kevin C. Dellsperger, and Tom R. Thomas: Exercise and diet induced weight loss improves measures of oxidative stress and insulin sensitivity in adults with characteristics of the metabolic syndrome
Am J Physiol Endocrinol Metab 293: E500-E506, 2007. First published May 1, 2007; doi:10.1152/ajpendo.00116.2007 [Abstract] [Full Text] [PDF]

Stephen E. Borst, Christine F. Conover, Christy S. Carter, Chris M. Gregory, Emanuele Marzetti, Christiaan Leeuwenburgh, Krista Vandenborne, and Thomas J. Wronski: Anabolic effects of testosterone are preserved during inhibition of 5 ${alpha}$ -reductase
Am J Physiol Endocrinol Metab 293: E507-E514, 2007. First published May 8, 2007; doi:10.1152/ajpendo.00130.2007 [Abstract] [Full Text] [PDF]

Makiko Fukaya, Akira Mizuno, Hidekazu Arai, Kazusa Muto, Takashi Uebanso, Kaoru Matsuo, Hironori Yamamoto, Yutaka Taketani, Toshio Doi, and Eiji Takeda: Mechanism of rapid-phase insulin response to elevation of portal glucose concentration
Am J Physiol Endocrinol Metab 293: E515-E522, 2007. First published May 1, 2007; doi:10.1152/ajpendo.00536.2006 [Abstract] [Full Text] [PDF]

H. J. Green, T. A. Duhamel, G. P. Holloway, J. W. Moule, J. Ouyang, D. Ranney, and A. R. Tupling: Muscle Na⁺-K⁺-ATPase response during 16 h of heavy intermittent cycle exercise
Am J Physiol Endocrinol Metab 293: E523-E530, 2007. First published May 8, 2007; doi:10.1152/ajpendo.00004.2007 [Abstract] [Full Text] [PDF]

María Elena Quintanilla, Lutske Tampier, Amalia Sapag, Ziomara Gerdtzen, and Yedy Israel: Sex differences, alcohol dehydrogenase, acetaldehyde burst, and aversion to ethanol in the rat: a systems perspective
Am J Physiol Endocrinol Metab 293: E531-E537, 2007. First published May 8, 2007; doi:10.1152/ajpendo.00187.2007 [Abstract] [Full Text] [PDF]

Jie Zhou, Mauren F. A. Livak, Michel Bernier, Denis C. Muller, Olga D. Carlson, Dariush Elahi, Stuart Maudsley, and Josephine M. Egan: Ubiquitination is involved in glucose-mediated downregulation of GIP receptors in islets
Am J Physiol Endocrinol Metab 293: E538-E547, 2007. First published May 15, 2007; doi:10.1152/ajpendo.00070.2007 [Abstract] [Full Text] [PDF]

S. M. Husted, M. O. Nielsen, M. P. Tygesen, A. Kiani, D. Blache, and K. L. Ingvartsen: Programming of intermediate metabolism in young lambs affected by late gestational maternal undernourishment
Am J Physiol Endocrinol Metab 293: E548-E557, 2007. First published May 15, 2007; doi:10.1152/ajpendo.00441.2006 [Abstract] [Full Text] [PDF]

Saman Abeysekara, Jonathan M. Naylor, Andrew W. A. Wassef, Ulyana Isak, and Gordon A. Zello: D-Lactic acid-induced neurotoxicity in a calf model
Am J Physiol Endocrinol Metab 293: E558-E565, 2007. First published May 15, 2007; doi:10.1152/ajpendo.00063.2007 [Abstract] [Full Text] [PDF]

Xiao-Xia Han, Adrian Chabowski, Narendra N. Tandon, Jorge Calles-Escandon, Jan F. C. Glatz, Joost J. F. P. Luiken, and Arend Bonen: Metabolic challenges reveal impaired fatty acid metabolism and translocation of FAT/CD36 but not FABPpm in obese Zucker rat muscle
Am J Physiol Endocrinol Metab 293: E566-E575, 2007. First published May 22, 2007; doi:10.1152/ajpendo.00106.2007 [Abstract] [Full Text] [PDF]

Wen Guo, Siu Wong, Weisheng Xie, Tianluo Lei, and Zhijun Luo: Palmitate modulates intracellular signaling, induces endoplasmic reticulum stress, and causes apoptosis in mouse 3T3-L1 and rat primary preadipocytes
Am J Physiol Endocrinol Metab 293: E576-E586, 2007. First published May 22, 2007; doi:10.1152/ajpendo.00523.2006 [Abstract] [Full Text] [PDF]

Lixin Li, Mark Naples, Hui Song, Ronghua Yuan, Feilu Ye, Sharmi Shafi, Khosrow Adeli, and Dominic S. Ng: LCAT-null mice develop improved hepatic insulin sensitivity through altered regulation of transcription factors and suppressors of cytokine signaling
Am J Physiol Endocrinol Metab 293: E587-E594, 2007. First published June 5, 2007; doi:10.1152/ajpendo.00278.2007 [Abstract] [Full Text] [PDF]

Asumthia S. Jeyapalan, Renan A. Orellana, Agus Suryawan, Pamela M. J. O'Connor, Hanh V. Nguyen, Jeffery Escobar, Jason W. Frank, and Teresa A. Davis: Glucose stimulates protein synthesis in skeletal muscle of neonatal pigs through an AMPK- and mTOR-independent process
Am J Physiol Endocrinol Metab 293: E595-E603, 2007. First published June 5, 2007; doi:10.1152/ajpendo.00121.2007 [Abstract] [Full Text] [PDF]

Birgitte Sloth, Louise Davidsen, Jens Juul Holst, Anne Flint, and Arne Astrup: Effect of subcutaneous injections of PYY_1-36 and PYY_3-36 on appetite, ad libitum energy intake, and plasma free fatty acid concentration in obese males
Am J Physiol Endocrinol Metab 293: E604-E609, 2007. First published June 12, 2007; doi:10.1152/ajpendo.00153.2007 [Abstract] [Full Text] [PDF]

TRANSLATIONAL PHYSIOLOGY:

Steven R. Smith, John E. Blundell, Colleen Burns, Cinzia Ellero, Brock E. Schroeder, Nicole C. Kesty, Kim S. Chen, Amy E. Halseth, Cameron W. Lush, and Christian Weyer: Pramlintide treatment reduces 24-h caloric intake and meal sizes and improves control of eating in obese subjects: a 6-wk translational research study
Am J Physiol Endocrinol Metab 293: E620-E627, 2007. First published May 15, 2007; doi:10.1152/ajpendo.00217.2007 [Abstract] [Full Text] [PDF]

INNOVATIVE METHODOLOGY:

Roman Hovorka, Harsha Jayatillake, Eduard Rogatsky, Vlad Tomuta, Tomas Hovorka, and Daniel T. Stein: Calculating glucose fluxes during meal tolerance test: a new computational approach
Am J Physiol Endocrinol Metab 293: E610-E619, 2007. First published May 22, 2007; doi:10.1152/ajpendo.00546.2006 [Abstract] [Full Text] [PDF]

Cover Caption:

Cover

Cover: Perivascular fibrosis in the transgenic (mRen2) 27 (Ren2) heart. Light microscopic image at ×40 of structural changes in left ventricle of the placebo-treated Ren2 control, an animal model of chronically elevated tissue of angiotensin II and renin-angiotensis system activation. The image depicts perivascular fibrosis, using VVG (Verhoeff-van Gieson) staining; the Verhoeff component of this two-part stain is specific for elastin fibers, whereas the van Gieson stain is specific for collagen. From Whaley-Connell A, Govindarajan G, Habibi J, Hayden MR, Cooper SA, Wei Y, Ma L, Qazi M, Link D, Karuparthi PR, Stump C, Ferrario C, Sowers JR. Angiotensin II-mediated oxidative stress promotes myocardial tissue remodeling in the transgenic (mRen2) 27 Ren2 rat. Am J Physiol Endocrinol Metab 293: E355-E363, 2007.