AJP - Endocrinology and Metabolism -- Table of Contents (August 1 2005, 289 [2])

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TRANSLATIONAL PHYSIOLOGY:

Anita M. Hennige, Umut Ozcan, Terumasa Okada, Ulupi S. Jhala, Markus Schubert, Morris F. White, and Rohit N. Kulkarni: Alterations in growth and apoptosis of insulin receptor substrate-1-deficient ${beta}$ -cells
Am J Physiol Endocrinol Metab 289: E337-E346, 2005. First published April 12, 2005; doi:10.1152/ajpendo.00032.2004 [Abstract] [Full Text] [PDF]

Madhusmita Misra, Karen K. Miller, Kelly Kuo, Kathryn Griffin, Victoria Stewart, Emily Hunter, David B. Herzog, and Anne Klibanski: Secretory dynamics of ghrelin in adolescent girls with anorexia nervosa and healthy adolescents
Am J Physiol Endocrinol Metab 289: E347-E356, 2005. First published March 8, 2005; doi:10.1152/ajpendo.00615.2004 [Abstract] [Full Text] [PDF]

INVITED REVIEWS:

Bharathi Raju and Philip E. Cryer: Maintenance of the postabsorptive plasma glucose concentration: insulin or insulin plus glucagon?
Am J Physiol Endocrinol Metab 289: E181-E186, 2005; doi:10.1152/ajpendo.00460.2004 [Abstract] [Full Text] [PDF]

Lily Q. Dong and Feng Liu: PDK2: the missing piece in the receptor tyrosine kinase signaling pathway puzzle
Am J Physiol Endocrinol Metab 289: E187-E196, 2005; doi:10.1152/ajpendo.00011.2005 [Abstract] [Full Text] [PDF]

ARTICLES:

Mark Paciga, Edward R. Hirvi, Kathi James, and Graham F. Wagner: Characterization of big stanniocalcin variants in mammalian adipocytes and adrenocortical cells
Am J Physiol Endocrinol Metab 289: E197-E205, 2005. First published March 1, 2005; doi:10.1152/ajpendo.00581.2004 [Abstract] [Full Text] [PDF]

L. Moseley, R. L. P. G. Jentjens, R. H. Waring, R. M. Harris, L. K. Harding, and A. E. Jeukendrup: Measurement of exogenous carbohydrate oxidation: a comparison of [U-¹⁴C]glucose and [U-¹³C]glucose tracers
Am J Physiol Endocrinol Metab 289: E206-E211, 2005. First published February 22, 2005; doi:10.1152/ajpendo.00423.2004 [Abstract] [Full Text] [PDF]

Ling-Ling Tsai, Yu-Che Tsai, Kai Hwang, Yu-Wen Huang, and Jeh-En Tzeng: Repeated light-dark shifts speed up body weight gain in male F344 rats
Am J Physiol Endocrinol Metab 289: E212-E217, 2005. First published March 1, 2005; doi:10.1152/ajpendo.00603.2004 [Abstract] [Full Text] [PDF]

Mary E. Rabaglia, Mark P. Gray-Keller, Brian L. Frey, Michael R. Shortreed, Lloyd M. Smith, and Alan D. Attie: ${alpha}$ -Ketoisocaproate-induced hypersecretion of insulin by islets from diabetes-susceptible mice
Am J Physiol Endocrinol Metab 289: E218-E224, 2005. First published March 1, 2005; doi:10.1152/ajpendo.00573.2004 [Abstract] [Full Text] [PDF]

Mary Courtney Moore, Kazuhiro Kimura, Haruki Shibata, Tsutomu Honjoh, Masayuki Saito, Carrie A. Everett, Marta S. Smith, and Alan D. Cherrington: Portal 5-hydroxytryptophan infusion enhances glucose disposal in conscious dogs
Am J Physiol Endocrinol Metab 289: E225-E231, 2005. First published March 8, 2005; doi:10.1152/ajpendo.00614.2004 [Abstract] [Full Text] [PDF]

Jaime M. Grubert, Margaret Lautz, D. Brooks Lacy, Mary C. Moore, Ben Farmer, Angelina Penaloza, Alan D. Cherrington, and Owen P. McGuinness: Impact of continuous and pulsatile insulin delivery on net hepatic glucose uptake
Am J Physiol Endocrinol Metab 289: E232-E240, 2005. First published March 8, 2005; doi:10.1152/ajpendo.00567.2004 [Abstract] [Full Text] [PDF]

Jérôme Ruzzin and Jørgen Jensen: Contraction activates glucose uptake and glycogen synthase normally in muscles from dexamethasone-treated rats
Am J Physiol Endocrinol Metab 289: E241-E250, 2005. First published March 1, 2005; doi:10.1152/ajpendo.00587.2004 [Abstract] [Full Text] [PDF]

Cora Weigert, Anita M. Hennige, Katrin Brodbeck, Hans U. Häring, and Erwin D. Schleicher: Interleukin-6 acts as insulin sensitizer on glycogen synthesis in human skeletal muscle cells by phosphorylation of Ser⁴⁷³ of Akt
Am J Physiol Endocrinol Metab 289: E251-E257, 2005. First published March 8, 2005; doi:10.1152/ajpendo.00448.2004 [Abstract] [Full Text] [PDF]

Deanna Aftab Guy, Darleen Sandoval, M. A. Richardson, Donna Tate, and Stephen N. Davis: Effects of glycemic control on target organ responses to epinephrine in type 1 diabetes
Am J Physiol Endocrinol Metab 289: E258-E265, 2005. First published March 22, 2005; doi:10.1152/ajpendo.00311.2004 [Abstract] [Full Text] [PDF]

James Gibney, Troels Wolthers, Gudmundur Johannsson, A. Margot Umpleby, and Ken K. Y. Ho: Growth hormone and testosterone interact positively to enhance protein and energy metabolism in hypopituitary men
Am J Physiol Endocrinol Metab 289: E266-E271, 2005. First published February 22, 2005; doi:10.1152/ajpendo.00483.2004 [Abstract] [Full Text] [PDF]

Wim Derave, Bert O. Eijnde, Monique Ramaekers, and Peter Hespel: No effects of lifelong creatine supplementation on sarcopenia in senescence-accelerated mice (SAMP8)
Am J Physiol Endocrinol Metab 289: E272-E277, 2005. First published February 22, 2005; doi:10.1152/ajpendo.00039.2005 [Abstract] [Full Text] [PDF]

Joost van der Hoek, Marlijn Waaijers, Peter M. van Koetsveld, Diana Sprij-Mooij, Richard A. Feelders, Herbert A. Schmid, Philippe Schoeffter, Daniel Hoyer, Davide Cervia, John E. Taylor, Michael D. Culler, Steven W. J. Lamberts, and Leo J. Hofland: Distinct functional properties of native somatostatin receptor subtype 5 compared with subtype 2 in the regulation of ACTH release by corticotroph tumor cells
Am J Physiol Endocrinol Metab 289: E278-E287, 2005. First published March 15, 2005; doi:10.1152/ajpendo.00004.2005 [Abstract] [Full Text] [PDF]

Zhengyi Tang, Rong Yu, Yarong Lu, A. F. Parlow, and Jun-Li Liu: Age-dependent onset of liver-specific IGF-I gene deficiency and its persistence in old age: implications for postnatal growth and insulin resistance in LID mice
Am J Physiol Endocrinol Metab 289: E288-E295, 2005. First published March 15, 2005; doi:10.1152/ajpendo.00494.2004 [Abstract] [Full Text] [PDF]

Manfred Bodenlenz, Lukas A. Schaupp, Tatjana Druml, Romana Sommer, Andrea Wutte, Helga C. Schaller, Frank Sinner, Paul Wach, and Thomas R. Pieber: Measurement of interstitial insulin in human adipose and muscle tissue under moderate hyperinsulinemia by means of direct interstitial access
Am J Physiol Endocrinol Metab 289: E296-E300, 2005. First published March 15, 2005; doi:10.1152/ajpendo.00431.2004 [Abstract] [Full Text] [PDF]

Preeti H. Jethwa, Caroline J. Small, Kirsty L. Smith, Asha Seth, Sarah J. Darch, Caroline R. Abbott, Kevin G. Murphy, Jeannie F. Todd, Mohammad A. Ghatei, and Stephen R. Bloom: Neuromedin U has a physiological role in the regulation of food intake and partially mediates the effects of leptin
Am J Physiol Endocrinol Metab 289: E301-E305, 2005. First published March 22, 2005; doi:10.1152/ajpendo.00404.2004 [Abstract] [Full Text] [PDF]

Matthew P. Harber, Simon Schenk, Ariel L. Barkan, and Jeffrey F. Horowitz: Alterations in carbohydrate metabolism in response to short-term dietary carbohydrate restriction
Am J Physiol Endocrinol Metab 289: E306-E312, 2005. First published March 29, 2005; doi:10.1152/ajpendo.00069.2005 [Abstract] [Full Text] [PDF]

Géraldine Parnaud, Eva Hammar, Dominique G. Rouiller, and Domenico Bosco: Inhibition of calpain blocks pancreatic ${beta}$ -cell spreading and insulin secretion
Am J Physiol Endocrinol Metab 289: E313-E321, 2005. First published March 22, 2005; doi:10.1152/ajpendo.00006.2005 [Abstract] [Full Text] [PDF]

Angelo Scuteri, Samer S. Najjar, Denis Muller, Reubin Andres, Christopher H. Morrell, Alan B. Zonderman, and Edward G. Lakatta: apoE4 allele and the natural history of cardiovascular risk factors
Am J Physiol Endocrinol Metab 289: E322-E327, 2005. First published March 15, 2005; doi:10.1152/ajpendo.00408.2004 [Abstract] [Full Text] [PDF]

Leonard S. Golfman, Christopher R. Wilson, Saumya Sharma, Mathias Burgmaier, Martin E. Young, Patrick H. Guthrie, Melissa Van Arsdall, Julia V. Adrogue, Kathleen K. Brown, and Heinrich Taegtmeyer: Activation of PPAR ${gamma}$ enhances myocardial glucose oxidation and improves contractile function in isolated working hearts of ZDF rats
Am J Physiol Endocrinol Metab 289: E328-E336, 2005. First published March 29, 2005; doi:10.1152/ajpendo.00055.2005 [Abstract] [Full Text] [PDF]

LETTERS TO THE EDITOR:

E. T. Poehlman: Letter of Apology for Falsification of Data
Am J Physiol Endocrinol Metab 289: E357-E357, 2005; doi:10.1152/ajpendo.00218.2005 [Full Text] [PDF]

CORRIGENDA:

: Corrigendum
Am J Physiol Endocrinol Metab 289: E358-E358, 2005; doi:10.1152/ajpendo.00217.2005 [Full Text] [PDF]

Cover Caption:

Cover Cover: Immunocytochemical localization of stanniocalcin (STC) ligand in adult male mouse adrenal. Immunocytochemistry revealed that the majority of STC was preferentially confined to steroidogenic cells in the 3 cortical layers (zonae glomerulosa, fasciculata, and reticularis) and much less so in medullary zone cells. Highlighted are staining differences between fasciculata (right), reticularis (middle), and medullary zone cells (left). Fasciculata zone cells are honeycombed in appearance due to large numbers of lipid droplets, each of which is coated with STC ligand. Reticularis zone cells are not honeycombed because of their fewer lipid droplets, yet are stained a darker brown by antiserum. In comparison, medullary zone cells are only weakly immunoreactive and appear gray. Relative levels of STC within the adrenal were matched by similar levels of STC mRNA and receptor (not shown). For tissue preparation, the organ was perfusion fixed in situ with 4% buffered paraformaldehyde and embedded in paraffin. Tissue sections were counterstained in hematoxylin after antibody staining. From M. Paciga, E. R. Hirvi, K. James, and G. F. Wagner. Characterization of big stanniocalcin variants in mammalian adipocytes and adrenocortical cells. Am J Physiol Endocrinol Metab 289: E197-E206, 2005.