MINIREVIEWS:

Andrea Caumo and Livio Luzi

First-phase insulin secretion: does it exist in real life? Considerations on shape and function
Am J Physiol Endocrinol Metab 287: E371-E385, 2004; doi:10.1152/ajpendo.00139.2003 [Abstract] [Full Text] [PDF]  

Gentle Chikani, Weifei Zhu, and Eric J. Smart

Lipids: potential regulators of nitric oxide generation
Am J Physiol Endocrinol Metab 287: E386-E389, 2004; doi:10.1152/ajpendo.00106.2004 [Abstract] [Full Text] [PDF]  

ARTICLES:

Laura E. Parton, Frédérique Diraison, Suzanne E. Neill, Sujoy K. Ghosh, Mark A. Rubino, John E. Bisi, Celia P. Briscoe, and Guy A. Rutter

Impact of PPAR overexpression and activation on pancreatic islet gene expression profile analyzed with oligonucleotide microarrays
Am J Physiol Endocrinol Metab 287: E390-E404, 2004. First published May 4, 2004; doi:10.1152/ajpendo.00016.2004 [Abstract] [Full Text] [PDF]  

Jun-Li Liu, Karen T. Coschigano, Katie Robertson, Mark Lipsett, Yubin Guo, John J. Kopchick, Ujendra Kumar, and Ye Lauren Liu

Disruption of growth hormone receptor gene causes diminished pancreatic islet size and increased insulin sensitivity in mice
Am J Physiol Endocrinol Metab 287: E405-E413, 2004. First published May 11, 2004; doi:10.1152/ajpendo.00423.2003 [Abstract] [Full Text] [PDF]  

Yuka Fujimoto, E. Patrick Donahue, and Masakazu Shiota

Defect in glucokinase translocation in Zucker diabetic fatty rats
Am J Physiol Endocrinol Metab 287: E414-E423, 2004. First published May 11, 2004; doi:10.1152/ajpendo.00575.2003 [Abstract] [Full Text] [PDF]  

Zhibin He, Tao Jiang, Zhuowei Wang, Moshe Levi, and Jinping Li

Modulation of carbohydrate response element-binding protein gene expression in 3T3-L1 adipocytes and rat adipose tissue
Am J Physiol Endocrinol Metab 287: E424-E430, 2004. First published April 20, 2004; doi:10.1152/ajpendo.00568.2003 [Abstract] [Full Text] [PDF]  

Ramona Trebbien, Letty Klarskov, Mette Olesen, Jens J. Holst, Richard D. Carr, and Carolyn F. Deacon

Neutral endopeptidase 24.11 is important for the degradation of both endogenous and exogenous glucagon in anesthetized pigs
Am J Physiol Endocrinol Metab 287: E431-E438, 2004. First published May 4, 2004; doi:10.1152/ajpendo.00353.2003 [Abstract] [Full Text] [PDF]  

Jennifer A. Mitchell, Oksana Shynlova, B. Lowell Langille, and Stephen J. Lye

Mechanical stretch and progesterone differentially regulate activator protein-1 transcription factors in primary rat myometrial smooth muscle cells
Am J Physiol Endocrinol Metab 287: E439-E445, 2004. First published May 4, 2004; doi:10.1152/ajpendo.00275.2003 [Abstract] [Full Text] [PDF]  

Marie-Laure Delporte, Samira Ait El Mkadem, Muriel Quisquater, and Sonia M. Brichard

Leptin treatment markedly increased plasma adiponectin but barely decreased plasma resistin of ob/ob mice
Am J Physiol Endocrinol Metab 287: E446-E453, 2004. First published May 4, 2004; doi:10.1152/ajpendo.00488.2003 [Abstract] [Full Text] [PDF]  

Dana Lee Wilkinson, Robert F. P. Bertolo, Janet A. Brunton, Anna K. Shoveller, Paul B. Pencharz, and Ronald O. Ball

Arginine synthesis is regulated by dietary arginine intake in the enterally fed neonatal piglet
Am J Physiol Endocrinol Metab 287: E454-E462, 2004. First published May 18, 2004; doi:10.1152/ajpendo.00342.2003 [Abstract] [Full Text] [PDF]  

Christophe Broca, Vincent Breil, Céline Cruciani-Guglielmacci, Michèle Manteghetti, Christine Rouault, Michel Derouet, Salwa Rizkalla, Bernard Pau, Pierre Petit, Gérard Ribes, Alain Ktorza, René Gross, Gérard Reach, and Mohammed Taouis

Insulinotropic agent ID-1101 (4-hydroxyisoleucine) activates insulin signaling in rat
Am J Physiol Endocrinol Metab 287: E463-E471, 2004. First published April 13, 2004; doi:10.1152/ajpendo.00163.2003 [Abstract] [Full Text] [PDF]  

Ndubueze C. Okereke, Larraine Huston-Presley, Saeid B. Amini, Satish Kalhan, and Patrick M. Catalano

Longitudinal changes in energy expenditure and body composition in obese women with normal and impaired glucose tolerance
Am J Physiol Endocrinol Metab 287: E472-E479, 2004. First published April 27, 2004; doi:10.1152/ajpendo.00589.2003 [Abstract] [Full Text] [PDF]  

Cynthia C. Connolly, Lisa N. Aglione, Marta S. Smith, D. Brooks Lacy, and Mary Courtney Moore

Pregnancy impairs the counterregulatory response to insulin-induced hypoglycemia in the dog
Am J Physiol Endocrinol Metab 287: E480-E488, 2004. First published May 4, 2004; doi:10.1152/ajpendo.00529.2003 [Abstract] [Full Text] [PDF]  

Wantanee Kriengsinyos, Linda J. Wykes, Laksiri A. Goonewardene, Ronald O. Ball, and Paul B. Pencharz

Phase of menstrual cycle affects lysine requirement in healthy women
Am J Physiol Endocrinol Metab 287: E489-E496, 2004; doi:10.1152/ajpendo.00262.2003 [Abstract] [Full Text] [PDF]  

Martin J. Stevens, Weixian Zhang, Fei Li, and Anders A. F. Sima

C-peptide corrects endoneurial blood flow but not oxidative stress in type 1 BB/Wor rats
Am J Physiol Endocrinol Metab 287: E497-E505, 2004. First published May 4, 2004; doi:10.1152/ajpendo.00048.2004 [Abstract] [Full Text] [PDF]  

Polyxeni Koutkia, Bridget Canavan, Jeff Breu, Michael L. Johnson, and Steven K. Grinspoon

Nocturnal ghrelin pulsatility and response to growth hormone secretagogues in healthy men
Am J Physiol Endocrinol Metab 287: E506-E512, 2004. First published May 11, 2004; doi:10.1152/ajpendo.00548.2003 [Abstract] [Full Text] [PDF]  

M. Sheffield-Moore, C. W. Yeckel, E. Volpi, S. E. Wolf, B. Morio, D. L. Chinkes, D. Paddon-Jones, and R. R. Wolfe

Postexercise protein metabolism in older and younger men following moderate-intensity aerobic exercise
Am J Physiol Endocrinol Metab 287: E513-E522, 2004. First published May 18, 2004; doi:10.1152/ajpendo.00334.2003 [Abstract] [Full Text] [PDF]  

David L. Lipschitz, William R. Crowley, and Steven L. Bealer

Differential sensitivity of intranuclear and systemic oxytocin release to central noradrenergic receptor stimulation during mid- and late gestation in rats
Am J Physiol Endocrinol Metab 287: E523-E528, 2004. First published May 18, 2004; doi:10.1152/ajpendo.00572.2003 [Abstract] [Full Text] [PDF]  

Vitoon Saengsirisuwan, Felipe R. Perez, Julie A. Sloniger, Thomas Maier, and Erik J. Henriksen

Interactions of exercise training and -lipoic acid on insulin signaling in skeletal muscle of obese Zucker rats
Am J Physiol Endocrinol Metab 287: E529-E536, 2004. First published April 6, 2004; doi:10.1152/ajpendo.00013.2004 [Abstract] [Full Text] [PDF]  

Sangeeta R. Kashyap, Renata Belfort, Rachele Berria, Swangjit Suraamornkul, Thongchai Pratipranawatr, Jean Finlayson, Andrea Barrentine, Mandeep Bajaj, Lawrence Mandarino, Ralph DeFronzo, and Kenneth Cusi

Discordant effects of a chronic physiological increase in plasma FFA on insulin signaling in healthy subjects with or without a family history of type 2 diabetes
Am J Physiol Endocrinol Metab 287: E537-E546, 2004. First published May 4, 2004; doi:10.1152/ajpendo.00541.2003 [Abstract] [Full Text] [PDF]  

Marina Malikova, Jun Shi, and Konstantin V. Kandror

V-type ATPase is involved in biogenesis of GLUT4 vesicles
Am J Physiol Endocrinol Metab 287: E547-E552, 2004. First published May 27, 2004; doi:10.1152/ajpendo.00571.2003 [Abstract] [Full Text] [PDF]  

Lubna Al-Khalili, Anna Krook, Juleen R. Zierath, and Gregory D. Cartee

Prior serum- and AICAR-induced AMPK activation in primary human myocytes does not lead to subsequent increase in insulin-stimulated glucose uptake
Am J Physiol Endocrinol Metab 287: E553-E557, 2004. First published May 18, 2004; doi:10.1152/ajpendo.00161.2004 [Abstract] [Full Text] [PDF]  

Luc J. C. van Loon, René Koopman, Ralph Manders, Walter van der Weegen, Gerrit P. van Kranenburg, and Hans A. Keizer

Intramyocellular lipid content in type 2 diabetes patients compared with overweight sedentary men and highly trained endurance athletes
Am J Physiol Endocrinol Metab 287: E558-E565, 2004. First published May 27, 2004; doi:10.1152/ajpendo.00464.2003 [Abstract] [Full Text] [PDF]  

Keiji Iida, Juan P. del Rincon, Dong-Sun Kim, Emina Itoh, Karen T. Coschigano, John J. Kopchick, and Michael O. Thorner

Regulation of full-length and truncated growth hormone (GH) receptor by GH in tissues of lit/lit or bovine GH transgenic mice
Am J Physiol Endocrinol Metab 287: E566-E573, 2004. First published May 27, 2004; doi:10.1152/ajpendo.00110.2004 [Abstract] [Full Text] [PDF]  

INNOVATIVE METHODOLOGY:

James G. Granneman, Pipeng Li, Yuyan Lu, and Jacqueline Tilak

Seeing the trees in the forest: selective electroporation of adipocytes within adipose tissue
Am J Physiol Endocrinol Metab 287: E574-E582, 2004. First published May 4, 2004; doi:10.1152/ajpendo.00567.2003 [Abstract] [Full Text] [PDF]  

REPORTS:

S. A. Stanley, K. G. Murphy, G. A. Bewick, W. M. Kong, J. Opacka-Juffry, J. V. Gardiner, M. Ghatei, C. J. Small, and S. R. Bloom

Regulation of rat pituitary cocaine- and amphetamine-regulated transcript (CART) by CRH and glucocorticoids
Am J Physiol Endocrinol Metab 287: E583-E590, 2004. First published May 11, 2004; doi:10.1152/ajpendo.00576.2003 [Abstract] [Full Text] [PDF]  

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