| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH |
|
|
|
|||||||
|
|||||||||
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
1 Exercise and Sports Science, University of Miami, Miami, Florida, United States
2 Integrative Biology, University of California, Berkeley, California, United States
* To whom correspondence should be addressed. E-mail: gbrooks{at}berkeley.edu.
We evaluated the hypothesis that net leg total free fatty acid (FFA), LDL cholesterol (LDL-C), and triglyceride (TG) uptake and HDL cholesterol (HDL-C) release during moderate intensity cycling exercise would be increased following endurance training. Eight sedentary men (26 ± 1 yr, 77.4 ± 3.7 kg) were studied in the postprandial state during 90 min of rest and 60 min of exercise twice before [45% and 65% peak oxygen consumption (VO2peak) and twice after 9 wk of endurance training (55% and 65% post training VO2peak). The transition from rest to exercise resulted in a shift from net leg total FFA release (-44±16) to uptake (193±49 µmolmin) that was unaffected by either exercise intensity or endurance training. The relative net leg release and uptake of individual FFA closely resembled their relative abundances in the plasma with approximately 21 and 41% of net leg total FFA uptake during exercise accounted for by palmitate (16:0) and oleate (18:1), respectively. Endurance training resulted in significant changes in arterial concentrations of HDL-C (49±5 vs. 52±5 mgdl-1, pre vs. post) and LDL-C (82±9 vs. 76±9 mgdl-1, pre vs. post), but there was no net TG or LDL-C uptake or HDL-C release across the resting or active leg before or after endurance training. In conclusion, endurance training favorably affects blood lipoprotein profiles even in young healthy normolipidemic men, but muscle contractions per se have little effect on net leg total FFA, LDL-C, or TG uptake or HDL-C release during moderate intensity cycling exercise.
This article has been cited by other articles:
|
|
 |
|
  C. G. C. Vinagre, E. S. Ficker, C. Finazzo, M. J. N. Alves, K. de Angelis, M. C. Irigoyen, C. E. Negrao, and R. C. Maranhao Enhanced removal from the plasma of LDL-like nanoemulsion cholesteryl ester in trained men compared with sedentary healthy men J Appl Physiol, October 1, 2007; 103(4): 1166 - 1171. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G. A. Wallis, A. L. Friedlander, K. A. Jacobs, M. A. Horning, J. A. Fattor, E. E. Wolfel, G. D. Lopaschuk, and G. A. Brooks Substantial working muscle glycerol turnover during two-legged cycle ergometry Am J Physiol Endocrinol Metab, October 1, 2007; 293(4): E950 - E957. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. L. Friedlander, K. A. Jacobs, J. A. Fattor, M. A. Horning, T. A. Hagobian, T. A. Bauer, E. E. Wolfel, and G. A. Brooks Contributions of working muscle to whole body lipid metabolism are altered by exercise intensity and training Am J Physiol Endocrinol Metab, January 1, 2007; 292(1): E107 - E116. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH |
| Visit Other APS Journals Online |
