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Fig. 1. Fatty acid kinetics (in g) over 24 h in a normal-weight (body mass index 22.5 kg/m2) man with 15% body fat and a normal-weight woman with 30% body fat are depicted. To make the calculations, we assume that 14, 8, and 2 h of the day are spent in the postabsorptive state, in the postprandial state, and doing physical activity at a level that would affect lipolysis and fat oxidation, respectively. Regional fatty acid metabolism is represented from legs to chest as lower body subcutaneous adipose tissue, visceral adipose tissue, and upper body subcutaneous adipose tissue. Green arrows represent regional meal fat storage via lipoprotein lipase-mediated pathways assuming a 75 g/day ingestion of meal fat. Blue arrows represent direct storage of free fatty acids (FFAs) into regional depots from the circulating FFA pool. Red arrows indicate regional flow of FFAs that enter the circulation via lipolysis. Oxidation of fat is indicated as CO2 production. Size of arrow is proportional to the contributory flow of FFAs to each pool. Illustrations of the male and female are reprinted with permission from the Mayo Foundation for Medical Education and Research.
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