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Am J Physiol Endocrinol Metab 287: E386-E389, 2004; doi:10.1152/ajpendo.00106.2004
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Fig. 1. Conceptual model of lipid-mediated effects on nitric oxide (NO) generation. oxLDL, oxidized LDL; cav1, caveolin-1; ER, estrogen receptor. The model illustrates several of the mechanisms by which lipoproteins and hypercholesterolemia can affect endothelial nitric oxide synthase (eNOS) activity.





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