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Am J Physiol Endocrinol Metab 284: E416-E423, 2003. First published October 15, 2002; doi:10.1152/ajpendo.0199.2001
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Vol. 284, Issue 2, E416-E423, February 2003

Potassium per kilogram fat-free mass and total body potassium: predictions from sex, age, and anthropometry

Ingrid Larsson, Anna Karin Lindroos, Markku Peltonen, and Lars Sjöström

Department of Body Composition and Metabolism, The Sahlgrenska Academy at Göteborg University, SE-41345 Goteborg, Sweden

Total body potassium (TBK) is located mainly intracellularly and constitutes an index of fat-free mass (FFM). The aim was to examine whether TBK and the TBK-to-FFM ratio (TBK/FFM) can be estimated from sex, age, weight, and height. A primary study group (164 males, 205 females) and a validation group (161 and 206), aged 37-61 yr, were randomly selected from the general population. TBK was determined by whole body counting, and FFM was obtained by dual-energy X-ray absorptiometry (DEXA; FFMDEXA). The primary study group was used to construct sex-specific equations predicting TBK and TBK/FFM from age, weight, and height. The equations were used to estimate TBK and TBK/FFM in the validation group. The estimates were compared with measured values. TBK in different age ranges was predicted, with errors ranging from 5.0 to 6.8%; errors for TBK/FFM ranged from 2.7 to 4.8%, respectively. By adding FFMDEXA as a fourth predictor, the error of the TBK prediction decreased by approximately two percentage units. In conclusion, TBK and TBK/FFM can be meaningfully estimated from sex, age, weight, and height.

body composition; dual-energy X-ray absorptiometry; potassium-40; total body potassium-to-fat-free mass ratio; randomly selected study groups





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