AJP - Endo Fuel your research with LabChart
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am J Physiol Endocrinol Metab 272: E1023-E1030, 1997;
0193-1849/97 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Okamura, K.
Right arrow Articles by Suzuki, M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Okamura, K.
Right arrow Articles by Suzuki, M.

AJP - Endocrinology and Metabolism, Vol 272, Issue 6 E1023-E1030, Copyright © 1997 by American Physiological Society

ARTICLES

Effect of amino acid and glucose administration during postexercise recovery on protein kinetics in dogs

K. Okamura, T. Doi, K. Hamada, M. Sakurai, K. Matsumoto, K. Imaizumi, Y. Yoshioka, S. Shimizu and M. Suzuki
Saga Research Institute, Otsuka Pharmaceutical Co., Ltd, Japan.

To examine the effect of the timing of amino acids (AA) and glucose (G) administration after exercise on protein kinetics, ten dogs fitted with chronic catheters in the artery and the femoral vein ran on a treadmill for 150 min. They were intraportally infused with a solution containing AA and G either right after (E) or 2 h after (L) the exercise. The protein kinetics were estimated using the arteriovenous difference of phenylalanine (Phe) coupled with the [2H5]Phe dilution method. The net balance of Phe across the hindlimb (HL) was negative after exercise. It became positive in E within 15 min after the start of the infusion, and it remained negative in L until the infusion was initiated. The uptake of Phe by the HL during the second half of the infusion period was higher in E than in L (10.9 +/- 6.6 vs. 5.4 +/- 2.3 nmol.kg-1.min-1, P = 0.049). During the infusion, protein synthesis in the HL was higher in E than in L (29.7 +/- 9.6 vs. 22.0 +/- 10.1 nmol.kg-1.min-1, P = 0.028), whereas proteolysis was comparable (18.7 +/- 5.7 vs. 16.5 +/- 11.1 nmol.kg-1.min-1. These results suggest that the early provision of the nutrients after exercise more effectively enhances protein accretion than nutrients administered later.


This article has been cited by other articles:


Home page
 Am. J. Physiol. Endocrinol. Metab.Home page
D. K. Levenhagen, J. D. Gresham, M. G. Carlson, D. J. Maron, M. J. Borel, and P. J. Flakoll
Postexercise nutrient intake timing in humans is critical to recovery of leg glucose and protein homeostasis
Am J Physiol Endocrinol Metab, June 1, 2001; 280(6): E982 - E993.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Endocrinol. Metab.Home page
S. M. Phillips, K. D. Tipton, A. A. Ferrando, and R. R. Wolfe
Resistance training reduces the acute exercise-induced increase in muscle protein turnover
Am J Physiol Endocrinol Metab, January 1, 1999; 276(1): E118 - E124.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online