AJP - Endo Fuel your research with LabChart
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am J Physiol Endocrinol Metab 269: E627-E635, 1995;
0193-1849/95 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Ramsay, T. G.
Right arrow Articles by Steele, N. C.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Ramsay, T. G.
Right arrow Articles by Steele, N. C.

AJP - Endocrinology and Metabolism, Vol 269, Issue 4 E627-E635, Copyright © 1995 by American Physiological Society

ARTICLES

Tissue IGF-I protein and mRNA responses to a single injection of somatotropin

T. G. Ramsay, I. B. Chung, S. M. Czerwinski, J. P. McMurtry, R. W. Rosebrough and N. C. Steele
Nonruminant Nutrition Laboratory, United States Department of Agriculture-Agricultural Research Service, Beltsville, Maryland 20705, USA.

Swine were divided into four groups of 11 animals at 40 kg body wt. Swine within a group were given a single porcine somatotropin (pST) injection (200 micrograms/kg) or buffer at 0800. Blood, liver (L), latissimus dorsi (LD), semitendinosus (STS), vastus lateralis (VL), dorsal subcutaneous (SQ), and perirenal (PR) adipose tissues were sampled at 0, 1, 2, 4, 8, 12, 16, and 24 h postinjection. Blood urea nitrogen was depressed by 16 h. Insulin was elevated by approximately 350% at 8 h. Lipogenic enzyme activities in adipose tissues were not affected by pST treatment. Insulin-like growth factor I (IGF-I) mRNA levels increased rapidly in SQ, PR, and L to a single pST administration, whereas they increased only slightly in VL. IGF-I mRNA concentrations in LD and STS were unaffected by pST treatment. IGF-I protein content of tissues changed little during the first 24 h postinjection. These data suggest that individual tissues differ in timing and degree of response to pST. Conflicting results reported after pST treatment could, in part, be due to tissue selection for sampling or sample timing.


This article has been cited by other articles:


Home page
 J ANIM SCIHome page
T. G. Ramsay and M. P. Richards
Hormonal regulation of leptin and leptin receptor expression in porcine subcutaneous adipose tissue
J Anim Sci, December 1, 2004; 82(12): 3486 - 3492.
[Abstract] [Full Text] [PDF]

Home page
 J. Nutr.Home page
F. A. Simmen, L. Badinga, M. L. Green, I. Kwak, S. Song, and R. C. M. Simmen
The Porcine Insulin-Like Growth Factor System: At the Interface of Nutrition, Growth and Reproduction
J. Nutr., February 1, 1998; 128(2): 315 - 315.
[Abstract] [Full Text]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online