AJP - Endo AJP: Lung Cellular and Molecular Physiology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
 QUICK SEARCH:   [advanced]


     


Am J Physiol Endocrinol Metab 267: E828-E836, 1994;
0193-1849/94 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Shanmugam, S.
Right arrow Articles by Gasc, J. M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Shanmugam, S.
Right arrow Articles by Gasc, J. M.

AJP - Endocrinology and Metabolism, Vol 267, Issue 6 E828-E836, Copyright © 1994 by American Physiological Society


ARTICLES

Ontogeny of the two angiotensin II type 1 receptor subtypes in rats

S. Shanmugam, P. Corvol and J. M. Gasc
Laboratoire de Medecine Experimentale, Institut National de la Sante et de la Recherche Medicale Unite 36-College de France, Paris.

The two subtypes (AT1A and AT1B) of the type 1 (AT1) angiotensin II receptor mRNA were localized by in situ hybridization in rat fetal tissues from day 11 to 19 of gestation and in the young rat from day 0 to 10 postpartum, by use of 35S-labeled cRNA probes. Both subtype mRNAs were present in the kidney and in the adrenal gland. Organs such as liver, lung, heart, and undifferentiated mesenchymes expressed only AT1A mRNA. In contrast to the adult, only AT1A subtype was expressed during fetal and postnatal periods in the pituitary gland. Large blood vessels (e.g., aorta and cerebral arteries) expressed exclusively AT1A mRNA during fetal stages. The expression of each subtype appears to be differentially regulated, in a tissue- and age-specific way. This spatotemporal regulation of AT1A and AT1B expression suggests that angiotensin II could act as a differentiation factor during organogenesis in addition to its classical role as a regulator of the cardiovascular system.


This article has been cited by other articles:


Home page
Am. J. Physiol. Regul. Integr. Comp. Physiol.Home page
J. H. Lee, S. Xia, and L. Ragolia
Upregulation of AT2 receptor and iNOS impairs angiotensin II-induced contraction without endothelium influence in young normotensive diabetic rats
Am J Physiol Regulatory Integrative Comp Physiol, July 1, 2008; 295(1): R144 - R154.
[Abstract] [Full Text] [PDF]


Home page
Physiol. Rev.Home page
M. Paul, A. Poyan Mehr, and R. Kreutz
Physiology of local Renin-Angiotensin systems.
Physiol Rev, July 1, 2006; 86(3): 747 - 803.
[Abstract] [Full Text] [PDF]


Home page
J. Physiol.Home page
V. Sahajpal and N. Ashton
Increased glomerular angiotensin II binding in rats exposed to a maternal low protein diet in utero
J. Physiol., February 15, 2005; 563(1): 193 - 201.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Physiol. Renal Physiol.Home page
D. Lasaitiene, P. Friberg, B. Sundelin, and Y. Chen
Neonatal RAS inhibition changes the phenotype of the developing thick ascending limb of Henle
Am J Physiol Renal Physiol, June 1, 2004; 286(6): F1144 - F1153.
[Abstract] [Full Text] [PDF]


Home page
Physiol. GenomicsHome page
M. PRIETO, S. DIPP, S. MELEG-SMITH, and S. S. EL-DAHR
Ureteric bud derivatives express angiotensinogen and AT1 receptors
Physiol Genomics, June 6, 2001; 6(1): 29 - 37.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Physiol. Renal Physiol.Home page
V. Gimonet, L. Bussieres, A. A. Medjebeur, B. Gasser, B. Lelongt, and K. Laborde
Nephrogenesis and angiotensin II receptor subtypes gene expression in the fetal lamb
Am J Physiol Renal Physiol, June 1, 1998; 274(6): F1062 - F1069.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Physiol. Heart Circ. Physiol.Home page
D. Lu, H. Yang, and M. K. Raizada
Attenuation of ANG II actions by adenovirus delivery of AT1 receptor antisense in neurons and SMC
Am J Physiol Heart Circ Physiol, February 1, 1998; 274(2): H719 - H727.
[Abstract] [Full Text] [PDF]


Home page
HypertensionHome page
S. Shanmugam, P. Corvol, and J.-M. Gasc
Angiotensin II Type 2 Receptor mRNA Expression in the Developing Cardiopulmonary System of the Rat
Hypertension, July 1, 1996; 28(1): 91 - 97.
[Abstract] [Full Text]


Home page
HypertensionHome page
D. Chansel, C. Llorens-Cortes, S. Vandermeersch, P. Pham, and R. Ardaillou
Regulation of Angiotensin II Receptor Subtypes by Dexamethasone in Rat Mesangial Cells
Hypertension, April 1, 1996; 27(4): 867 - 874.
[Abstract] [Full Text]




HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online