AJP - Endo AJP: Heart and Circulatory Physiology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am J Physiol Endocrinol Metab 261: E214-E220, 1991;
0193-1849/91 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Kjaer, M.
Right arrow Articles by Mitchell, J. H.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Kjaer, M.
Right arrow Articles by Mitchell, J. H.

AJP - Endocrinology and Metabolism, Vol 261, Issue 2 E214-E220, Copyright © 1991 by American Physiological Society

ARTICLES

Hormonal, metabolic, and cardiovascular responses to static exercise in humans: influence of epidural anesthesia

M. Kjaer, N. H. Secher, F. W. Bach, H. Galbo, D. R. Reeves Jr and J. H. Mitchell
Department of Anesthesia, Rigshospitalet, Denmark.

To determine the role of reflex neural mechanisms for hormonal, metabolic, heart rate (HR), and blood pressure (MABP) changes during static exercise, seven health young males performed 10-min periods of two-legged static knee extension both during control and during epidural anesthesia. Comparisons were made at identical absolute (29 Nm) and relative [15% maximal voluntary contraction (MVC)] force. Afferent nerve blockade was verified by hypesthesia below T10-T12 and attenuated postexercise ischemic pressor response. Leg strength was reduced to 67 +/- 5% of control. At same relative force, increases in MABP and HR occurred more rapidly without than with epidural anesthesia (P less than 0.05). This difference was diminished during identical absolute force. Changes in plasma concentrations of catecholamines followed the pattern of HR and MABP responses, with differences between epidural and control experiments being most pronounced early in the work period. Plasma beta-endorphin was elevated only after control exercise. No response at 15% MVC was found for growth hormone, adrenocorticotropic hormone, insulin, glucagon, cortisol, glycerol, free fatty acids, or glucose (P greater than 0.05). In conclusion, during static exercise with large muscle groups and moderate relative force, modest changes in plasma hormones and metabolites take place. Furthermore, afferent nervous feedback from contracting muscles is important in regulation of blood pressure, heart rate, and catecholamine responses during static exercise in humans.


This article has been cited by other articles:


Home page
 Am. J. Physiol. Regul. Integr. Comp. Physiol.Home page
M. Kjar, B. Hanel, L. Worm, G. Perko, S. F. Lewis, K. Sahlin, H. Galbo, and N. H. Secher
Cardiovascular and neuroendocrine responses to exercise in hypoxia during impaired neural feedback from muscle
Am J Physiol Regulatory Integrative Comp Physiol, July 1, 1999; 277(1): R76 - R85.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
T. Nishiyasu, N. Tan, K. Morimoto, R. Sone, and N. Murakami
Cardiovascular and humoral responses to sustained muscle metaboreflex activation in humans
J Appl Physiol, January 1, 1998; 84(1): 116 - 122.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Endocrinol. Metab.Home page
S. M. Weltan, A. N. Bosch, S. C. Dennis, and T. D. Noakes
Influence of muscle glycogen content on metabolic regulation
Am J Physiol Endocrinol Metab, January 1, 1998; 274(1): E72 - E82.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online