AJP - Endo Fuel your research with LabChart
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am J Physiol Endocrinol Metab 257: E855-E859, 1989;
0193-1849/89 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Lavoie, J. M.
Right arrow Articles by Doiron, B.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Lavoie, J. M.
Right arrow Articles by Doiron, B.

AJP - Endocrinology and Metabolism, Vol 257, Issue 6 E855-E859, Copyright © 1989 by American Physiological Society

ARTICLES

Influence of hepatic vagus nerve on pancreatic hormone secretion during exercise

J. M. Lavoie, S. Cardin and B. Doiron
Department d'Education Physique, Universite de Montreal, Quebec, Canada.

There has been recent evidence that the liver through the hepatic vagus nerve may influence the resting levels of plasma insulin in adrenalectomized rats. The present investigation was designed to evaluate whether such a relationship exists during physical exercise. To this end, the effects of a selective hepatic vagotomy on portal and peripheral insulin and on peripheral glucagon concentrations were studied after a 30-min treadmill run (26 m/min, 0% grade) in adrenodemelludated rats. Hepatic vagotomy was associated with small but significantly higher (P less than 0.05) levels of liver glycogen and blood glucose at rest and after exercise. No significant differences were observed between hepatic-vagotomized and sham-operated rats in resting insulin, glucagon, and plasma norepinephrine concentrations. Peripheral plasma insulin levels after exercise were significantly higher (P less than 0.01) in hepatic-vagotomized than in sham-operated rats [172 +/- 20 vs. 108 +/- 10 (SE) pmol/l]. Exercise was also associated with a significantly lower peripheral glucagon (P less than 0.01) and norepinephrine (P less than 0.05) levels in hepatic-vagotomized compared with sham-operated rats. These results indicate a role for the hepatic vagus nerve in the regulation of pancreatic islet secretion during exercise, possibly by contributing to the increase in sympathetic activity.


This article has been cited by other articles:


Home page
 J. Appl. Physiol.Home page
J.-M. Lavoie, Y. Fillion, K. Couturier, and P. Corriveau
Exercise Effects on Muscle Insulin Signaling and Action: Selected Contribution: Evidence that the decrease in liver glycogen is associated with the exercise-induced increase in IGFBP-1
J Appl Physiol, August 1, 2002; 93(2): 798 - 804.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Regul. Integr. Comp. Physiol.Home page
M. G. Latour, A. Brault, P.-M. Huet, and J.-M. Lavoie
Effects of acute physical exercise on hepatocyte volume and function in rat
Am J Physiol Regulatory Integrative Comp Physiol, May 1, 1999; 276(5): R1258 - R1264.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
M. G. Latour, F. Desy, C. Warren, and J.-M. Lavoie
Effects of hepatic portal infusion of deionized water on metabolic and hormonal responses to exercise in rats
J Appl Physiol, May 1, 1998; 84(5): 1653 - 1660.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
M. Tadjore, R. Bergeron, M. Latour, F. Desy, C. Warren, and J.-M. Lavoie
Effects of dietary manipulations and glucose infusion on glucagon response during exercise in rats
J Appl Physiol, July 1, 1997; 83(1): 148 - 152.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online