AJP - Endo Fuel your research with LabChart
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am J Physiol Endocrinol Metab 253: E584-E590, 1987;
0193-1849/87 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Cobelli, C.
Right arrow Articles by Jensen, I.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Cobelli, C.
Right arrow Articles by Jensen, I.

AJP - Endocrinology and Metabolism, Vol 253, Issue 5 E584-E590, Copyright © 1987 by American Physiological Society

ARTICLES

Reconstructing the rate of appearance of subcutaneous insulin by deconvolution

C. Cobelli, A. Mari, S. Del Prato, S. De Kreutzenberg, R. Nosadini and I. Jensen
Department of Electronics and Informatics, University of Padua, Italy.

In this paper a deconvolution scheme is presented to reconstruct the rate of appearance of subcutaneously injected insulin. Relevant aspects of experiment design are briefly described. Intravenous insulin kinetics are modeled to determine the impulse response of the system. The deconvolution problem is not ill conditioned and is solved using a least-squares method without imposing constraints on the input. An estimate of the error of the reconstructed input is provided. The reliability of the deconvolution scheme is tested by means of an independent validation study. Finally, the different sources of error that affect the method are discussed, and a figure of the global error is derived.


This article has been cited by other articles:


Home page
 Am. J. Physiol. Endocrinol. Metab.Home page
A. Natali, A. Gastaldelli, A. Q. Galvan, A. M. Sironi, D. Ciociaro, G. Sanna, P. Rosenzweig, and E. Ferrannini
Effects of acute alpha 2-blockade on insulin action and secretion in humans
Am J Physiol Endocrinol Metab, January 1, 1998; 274(1): E57 - E64.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online