AJP - Endo Journal of Applied Physiology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am J Physiol Endocrinol Metab 247: E574-E580, 1984;
0193-1849/84 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Gilbert, M.
Right arrow Articles by Bouisset, M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Gilbert, M.
Right arrow Articles by Bouisset, M.

AJP - Endocrinology and Metabolism, Vol 247, Issue 5 574-E580, Copyright © 1984 by American Physiological Society

ARTICLES

Uterine blood flow and substrate uptake in conscious rabbit during late gestation

M. Gilbert, S. Hauguel and M. Bouisset

The aim of this study was the quantitation of the metabolic demands of the uterus in rabbits between days 24 and 30 of gestation, a time at which there is a fourfold increase in fetal weight. Serial measurements of substrate concentrations in maternal artery and uterine vein were performed over this period. Uterine blood flow was measured on days 24 and 30. Uterine substrate uptake was calculated by application of the Fick principle. Over the gestation range studied, the absolute uterine blood flow increased proportionally to the uterine weight gain. The uterine arteriovenous differences for glucose (G), lactate (L), free fatty acids (FFA), ketone bodies (KB), and oxygen (O2) were constant throughout the study. At both gestational ages, the weight-specific uterine substrate consumption (G, FFA, KB, O2) and production (L) were respectively similar. On days 24 and 30 the amount of G directed to the gravid uterus represented approximately 13 and approximately 36% of the maternal glucose turnover rate, respectively. The maximum contributions of G and FFA to the uterine oxygen consumption on day 24 were 80 and 30%, respectively. We have thus confirmed that at term the gravid uterus is a site of high glucose consumption. Finally, we demonstrated that in a nonruminant species, FFA would be a substantial source of carbon.


This article has been cited by other articles:


Home page
 J. Appl. Physiol.Home page
A. E. Nesbitt, R. J. Murphy, and K. P. O'Hagan
Effect of gestational stage on uterine artery blood flow during exercise in rabbits
J Appl Physiol, December 1, 2005; 99(6): 2159 - 2165.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Regul. Integr. Comp. Physiol.Home page
K. P. O'Hagan and J. A. Alberts
Uterine artery blood flow and renal sympathetic nerve activity during exercise in rabbit pregnancy
Am J Physiol Regulatory Integrative Comp Physiol, November 1, 2003; 285(5): R1135 - R1144.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Regul. Integr. Comp. Physiol.Home page
V. L. Brooks, C. M. Kane, and L. S. Welch
Regional conductance changes during hemorrhage in pregnant and nonpregnant conscious rabbits
Am J Physiol Regulatory Integrative Comp Physiol, September 1, 1999; 277(3): R675 - R681.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online