AJP - Endo Fuel your research with LabChart
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am J Physiol Endocrinol Metab 238: E507-E510, 1980;
0193-1849/80 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Baran, D. T.
Right arrow Articles by Avioli, L. V.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Baran, D. T.
Right arrow Articles by Avioli, L. V.

AJP - Endocrinology and Metabolism, Vol 238, Issue 6 507-E510, Copyright © 1980 by American Physiological Society

ARTICLES

Effect of alcohol ingestion on bone and mineral metabolism in rats

D. T. Baran, S. L. Teitelbaum, M. A. Bergfeld, G. Parker, E. M. Cruvant and L. V. Avioli

Chronic ethanol administration to growing rats for 56 days resulted in circulating levels of 140 mg/dl, approximating concentrations that characterize alcoholic intoxication in man. This degree of alcohol ingestion, although without gross or histological effect on the liver or testicles, was attended by decreased trabecular bone volume despite a normal rate of skeletal mineralization as measured by time-spaced tetracycline labeling. Concomitant serum levels of calcium, phosphate, magnesium, creatinine, glutamic oxalacetic transaminase, alkaline phosphatase, testosterone, and 25-hydroxyvitamin D were normal. Although alcohol treatment was associated with a significant decrease in urinary calcium excretion, it had no effect on phosphate excretion nor on its renal tubular reabsorption. The data reveal that circulating levels of alcohol that do not result in hepatic or testicular injury are toxic for bone.


This article has been cited by other articles:


Home page
 Rheumatology (Oxford)Home page
N. Sofat and A. Keat
Alcohol intake in rheumatic disease: good or bad?
Rheumatology, February 1, 2002; 41(2): 125 - 128.
[Full Text] [PDF]

Home page
 Alcohol AlcoholHome page
D. A. Chakkalakal, J. R. Novak, E. D. Fritz, T. J. Mollner, D. L. McVicker, D. L. Lybarger, M. H. McGuire, and T. M. Donohue Jr
CHRONIC ETHANOL CONSUMPTION RESULTS IN DEFICIENT BONE REPAIR IN RATS
Alcohol Alcohol., January 1, 2002; 37(1): 13 - 20.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online