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Am J Physiol Endocrinol Metab 234: E480-E483, 1978;
0193-1849/78 $5.00
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AJP: Endocrinology and Metabolism, Vol 234, Issue 5, E480-E483
Copyright © 1978 by American Physiological Society

ARTICLES

Immunofluorescent localization of renin in mouse submaxillary gland and kidney

JW Menzie, LH Hoffman, and AM Michelakis

An antibody prepared against purified submaxillary renin was used to determine the site of renin concentration in male mice using immunofluorescent localization. The results provide direct evidence that the granular tubules of the submaxillary glands are the source of submaxillary renin. The antibody against submaxillary renin cross-reacts with kidney renin as evidenced by immunofluorescent localization in the juxtaglomerular apparatus of mouse kidney.




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